59-42-7
59-42-7 結(jié)構(gòu)式
基本信息
去氧腎上腺素堿
去羥腎上腺素
去氧腎上腺
新交感酚
新辛內(nèi)井林
L-PHENYLEPHRINE
(-)-PHENYLEPHRINE
PHENYLEPHRINE BASE
(-)-m-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol
(-)-m-hydroxy-alpha-(methylaminomethyl)benzylalcohol
(-)-m-oxedrine
(R)-3-Hydroxy-alpha-[(methylamino)methyl]benzenemethanol hydrochloride
(r)-benzenemethano
(r)-phenylephrine
Adrianol
Ak-dilate
Ak-nefrin
Alcon efrin
Benzyl alcohol, m-hydroxy-alpha-((methylamino)methyl)-, (-)-
Biomydrin
component of Cerose dm
component of Comhist
component of Cyclomydril
component of Decongestant
物理化學(xué)性質(zhì)
安全數(shù)據(jù)
知名試劑公司產(chǎn)品信息
L-Phenylephrine,>98.0%(T)(59-42-7)
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱(chēng) | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/08/19 | HY-B0769 | 去氧腎上腺素堿 Phenylephrine | 59-42-7 | 500mg | 500元 |
| 2024/08/19 | P0395 | L-苯腎上腺素 L-Phenylephrine | 59-42-7 | 5G | 720元 |
| 2024/08/19 | HY-B0769 | 去氧腎上腺素堿 Phenylephrine | 59-42-7 | 10mM * 1mLin DMSO | 550元 |
常見(jiàn)問(wèn)題列表
(R)-(-)-Phenylephrine is a selective α 1 -adrenoceptor agonist with pK i values of 5.86, 4.87 and 4.70 for α 1D , α 1B and α 1A receptors respectively. Phenylephrine promotes cardiac fibroblast proliferation. Phenylephrine activates CaN and evokes NFAT3 nuclear translocation. It suggests that the Ca( 2+ )/CaN/NFAT pathway mediates phenylephrine -induced cardiac fibroblast proliferation, and this pathway might be a possible therapeutic target in cardiac fibrosis.
Perfusion of hearts with 100 μM phenylephrine causes a rapid (maximal at 10 min) 12-fold activation of two p38-MAPK isoforms. α 1 -adrenoceptor agonists such as phenylephrine increase the contractility of the heart. Phenylephrine also activates SAPKs/JNKs in neonatal ventricular myocytes. Phenylephrine could increase the alveolar fluid clearance in high tidal volume-ventilated rats and accelerate the absorption of pulmonary edema.