552-58-9
552-58-9 結構式
基本信息
毛綱草酚
3',4',5,7-四羥二氫黃酮
3',4',5,7-TETRAHYDROXYFLAVANONE
5,7,3',4'-TETRAHYDROXYFLAVANONE
ERIODICTYOL
(S)-3',4',5,7-TETRAHYDROXYFLAVANONE
(S)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4-benzopyrone
(2S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-chroman-4-one
ERIODICTYOL(SH)
ERIODICTIOL
ERIODICTYOL hplc
ERIODICTYOL WITH HPLC
(2S)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-1-benzopyran-4-one
(2S)-2α-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-1-benzopyran-4-one
(S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one
物理化學性質
常見問題列表
圣草酚能抗菌、抗炎，在糖尿病的發(fā)病機制中起著至關重要的作用，可以抑制 immunoglobulin E(Ig E)/antigen (Ag)誘導I型過敏反應，同時具有止痛及溫熱功效。
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Human Endogenous Metabolite
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Eriodictyol is a flavonoid isolated from the Chinese herb, with antioxidant and anti-inflammatory activity. Eriodictyol (20, 40, 80 μM) protects primary cultured cortical neurons against Aβ 25-35 -induced cytotoxicity and cell apoptosis via the Nrf2/ARE pathway. Eriodictyol (80 μM) induces nuclear expression of Nrf2 and the expression of ARE-regulated genes in primary cultured cortical neurons.
Eriodictyol shows protective effect against LPS-induced acute lung injury (ALI). Eriodictyol (30 mg/kg, p.o.) decreases the production of inflammatory cytokines, elevates survival rate, and decreases oxidative stress levels in LPS-induced ALI mice. Eriodictyol inhibits MPO activity and inflammatory neutrophil accumulation in the lung tissues. Eriodictyol treatment also enhances Trx1 expression by upregulating the Nrf2 expression in lung tissues.