51-98-9
基本信息
炔諾酮醋酸酯
17β-羥基9-去甲-17α-孕甾-4-烯-20-炔-3-酮-17-醋酸酯
17Α-乙炔基-17Β-羥基雌甾-4-烯-3-酮17-醋酸酯
17Α-乙炔基雌甾-4-烯-17Β-醇-3-酮17-醋酸酯
17Β-乙酰氧基-17Α-乙炔基雌甾-4-烯-3-酮
17ALPHA-ETHYNYL-17BETA-HYDROXY-19-NOR-4-ANDROSTEN-3-ONE 17-ACETATE
17ALPHA-ETHYNYL-19-NORTESTOSTERONE 17BETA-ACETATE
17ALPHA-ETHYNYL-19-NORTESTOSTERONE ACETATE
17-hydroxy-19-nor-17a-4-pregnen-20-yn-3-one acetate
17-HYDROXY-19-NOR-17ALPHA-4-PREGNEN-20-YN-3-ONE ACETATE
19-NOR-17ALPHA-ETHYNYLTESTOSTERONE ACETATE
19-NORESTHISTERONE ACETATE
19-NORETHINDRONE ACETATE
19-NORETHISTERONE 17-ACETATE
19-NORETHISTERONE ACETATE
4-ESTREN-17ALPHA-ETHYNYL-17BETA-OL-3-ONE 17-ACETATE
4-ESTREN-17-ALPHA-ETHYNYL-17-BETA-OL-3-ONE ACETATE
ACETIC ACID 17-ETHYNYL-13-METHYL-3-OXO-2,3,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPE
NORETHINDRONE ACETATE
NORETHISTERONE ACETATE
(17-alpha)-17-(Acetyloxy)-19-norpregn-4-en-20-yn-3-one
(17α)-17-(acetyloxy)-19-norpregn-4-en-20-yn-3-one
17-acetoxy-19-nor-17-alpha-pregn-4-en-20-yn-3-on
17-acetoxy-19-nor-17-alpha-pregn-4-en-20-yn-3-one
物理化學(xué)性質(zhì)
常見問題列表
已知或疑有乳癌、雌激素依賴性腫瘤,有乳癌病史者,代謝性卟啉病患者。
Progesterone Receptor
Norethindrone acetate could be a cost-effective alternative with relatively mild side effects in the treatment of symptomatic endometriosis. Subjects treated with norethindrone acetate obtain dysmenorrhea and noncyclic pelvic pain relief. Norethindrone acetate alone is a well-tolerated, effective option to manage pain and bleeding for all stages of endometriosis. Post-Norethindrone acetate bleeding scores are improved regardless of prior hormonal regimen, and post-Norethindrone acetate pain scores improved in all patients except for those previously prescribed GnRH-agonist plus add-back. Norethindrone acetate shows low acute toxicity in experimental animals and is consistent with the lack of toxicity seen in humans. Administration of norethindrone acetate alone to rodents at several multiples of the human dose results in no treatment related mortality, hematological changes, behavioral changes, or organ pathology. Norethindrone acetate administration leads to significant and proportional reductions of the concentrations of triglycerides, cholesterol and phospholipids of plasma lipoproteins of density <1.006 of rats fed a high carbohydrate diet. Norethindrone acetate (0.1 mM) also significantly inhibits the incorporation of both palmitate and glycerol into triglycerides of isolated hepatocytes from fed rats.