434-07-1
中文名稱
羥甲烯龍
英文名稱
Oxymetholone
CAS
434-07-1
EINECS 編號
207-098-6
分子式
C21H32O3
MDL 編號
MFCD00869395
分子量
332.48
MOL 文件
434-07-1.mol
更新日期
2024/08/07 13:06:02
434-07-1 結(jié)構(gòu)式
基本信息
中文別名
康復(fù)龍羥甲烯龍
17β-羥基-2-羥亞甲基-17α-甲基-5α-雄甾(烷)-3-酮
2-羥亞甲基-17α-甲基-5α-雄甾(烷)-17β-醇-3-酮
羥甲睪丸素
羥甲稀龍
羥次甲氫龍
英文別名
17BETA-HYDROXY-2-(HYDROXYMETHYLENE)-17-METHYL-5ALPHA-ANDROSTAN-3-ONE17b-hydroxy-2-hydroxymethylene-17a-methyl-3-androstanone
4,5-dihydro-2-hydroxymethylene-17-a-methyltestosterone
5ALPHA-ANDROSTAN-17ALPHA-METHYL-17BETA-OL-2-HYDROXYMETHYLENE-3-ONE
5-ALPHA-ANDROSTAN-2-HYDROXYMETHYLENE-17-ALPHA-METHYL-17-BETA-OL-3-ONE
ANASTERONE
OXYMETHOLONE
17-alpha-Methyl-2-hydroxymethylene-17-hydroxy-5-alpha-androstan-3-one
17-beta-androstan-3-one,17-hydroxy-2-(hydroxymethylene)-17-methyl-5-alph
17-beta-Hydroxy-2-(hydroxymethylene)-17-alpha-methyl-5-alpha-androstan-3-one
17-beta-hydroxy-2-(hydroxymethylene)-17-methyl-5-alpha-androstan-3-on
17beta-hydroxy-2-(hydroxymethylene)-17-methyl-5alpha-androstan-3-on
17-beta-Hydroxy-2-hydroxymethylene-17-alpha-methyl-3-androstanone
17-hydroxy-2-(hydroxymethylene)-17-methyl-,(alpha,17beta)-androstan-3-on
17-Hydroxy-2-(hydroxymethylene)-17-methyl-5-alpha-17-beta-androst-3-one
17-Hydroxy-2-(hydroxymethylene)-17-methylandrostan-3-one
17-Hydroxy-2-hydroxymethylene-17-methyl-5-androstan-3-one
17-hydroxy-5-alpha-androstan-3-one
2-(hydroxymethylene)-17-alpha-methyldihydrotestosterone
2-(hydroxymethylene)-17-methyldihydrotestosterone
所屬類別
原料藥：雄激素及同化激素類藥物理化學(xué)性質(zhì)
外觀性狀白色結(jié)晶性粉末，無嗅。熔點173-176℃（178-180℃）。[α]D+38°（氯仿），不溶于水，易溶于氯仿，溶于二氧六環(huán)、植物油，略溶于乙醇、乙醚。
熔點172-180°C
比旋光度34 º
沸點409.59°C (rough estimate)
密度1.0834 (rough estimate)
折射率38 ° (C=1, CHCl3)
儲存條件2-8°C
溶解度H2O: ≤0.5 mg/mL
酸度系數(shù)(pKa)5.28±0.70(Predicted)
形態(tài)solid
顏色white to light yellow
水溶解性<0.1 g/100 mL at 23 ºC
Merck6967
穩(wěn)定性可能對光敏感。易燃。與強氧化劑不相容。
InChIKeyICMWWNHDUZJFDW-CCTJMHFWSA-N
CAS 數(shù)據(jù)庫434-07-1(CAS DataBase Reference)
NIST化學(xué)物質(zhì)信息Oxymetholone(434-07-1)
EPA化學(xué)物質(zhì)信息Oxymetholone (434-07-1)
安全數(shù)據(jù)
警示詞警告
危險性描述H351-H361
防范說明P201-P308+P313
危險品標(biāo)志T
危險類別碼R40-R63
WGK Germany3
RTECS號BV8060000
海關(guān)編碼29372900
毒害物質(zhì)數(shù)據(jù)434-07-1(Hazardous Substances Data)
毒性TDLo orl-hmn: 46 mg/kg/14W-I:LIV JAMAAP 240,243,78
應(yīng)用領(lǐng)域
用途一
康力龍的中間體。本身為蛋白同化激素類藥物，能促進(jìn)蛋白質(zhì)合成和抑制蛋白質(zhì)異生，并能降低血膽固醇、減少鈣磷排泄和減輕骨髓抑制，促進(jìn)發(fā)育，促進(jìn)組織新生和肉芽形成。對腎上腺皮質(zhì)激素長期使用引起的腎上腺皮質(zhì)功能減退有預(yù)防及對抗作用。知名試劑公司產(chǎn)品信息
Sigma Aldrich
434-07-1(sigmaaldrich)TCI Shanghai
康復(fù)龍Oxymetholone,>98.0%(GC)(434-07-1)