20315-25-7
20315-25-7 結(jié)構(gòu)式
基本信息
原矢車菊素B1
原花青素B1對照品
原花青素(OPC)
原花青素B1(標準品)
原花青素B1(95%)
原花青素 B1, 來源于葡萄籽
順式,反式′′-4,8′′-二-(3,3′,4′,5,7-五羥基黃烷)
PROCYANIDIN A2(SH)
PROCYANIDIN B1(RG)
PROCYANIDINDIMERB1
Proanthocyanidin B1
(4→8)-Procyanidin B1
Procyanidin Impurity 2
PROCYANIDIN B1 USP/EP/BP
EPICATECHIN(4B-8)CATECHIN
EPICATECHIN(4BETA->8)CATECHIN
物理化學性質(zhì)
應(yīng)用領(lǐng)域
藥理藥效:抗氧活性、抑制腫瘤作用。
原花青素B1是一種B型原花青素，存在于錫蘭肉桂中，具有抗炎，抗氧化，抗腫瘤，保護心血管的作用。
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2024/11/11 | XW203152571 | 原花青素B1 procyanidin b1;cis,trans-4,8''-bi-(3,3',4',5,7-pentahydroxyflavane) | 20315-25-7 | 5MG | 879元 |
| 2024/11/08 | HY-N0795 | 原花青素B1 Procyanidin B1 | 20315-25-7 | 1mg | 600元 |
| 2024/11/08 | HY-N0795 | 原花青素B1 Procyanidin B1 | 20315-25-7 | 5mg | 1200元 |
常見問題列表
Procyanidin B1 is a polyphenolic flavonoid isolated from fruits and fruit juices, binds to TLR4/MD-2 complex, and has anti-inflammatory activity. Procyanidin B1 causes cellular toxicity at concentrations >100 μg/mL. Procyanidin B1 (100 μg/mL) inhibits LPS-induced TNF-α production, and expression of MD-2, TRAF6, NF-κB mRNA, phosphorylated p38 MAPK and NF-κB protein in THP1 cells. Procyanidin B1 (50-100 μM) protects against Aβ oligomer-induced neuronal death. Procyanidin B1 potently inhibits the activation of caspase-3 at 100 μM, caspase-8 at concentrations of 30, 50, and 100 μM and caspase-9 at concentrations of 10, 30, 50, and 100 μM. Procyanidin B1 (10, 20, 30 μM) significantly and dose-dependently induces expression of ACO and CPT1, with no obvious effect on mRNA expression of PPARα.