1445-07-4
中文名稱
假尿苷
英文名稱
BETA-PSEUDOURIDINE
CAS
1445-07-4
分子式
C9H12N2O6
分子量
244.2
MOL 文件
1445-07-4.mol
更新日期
2025/01/26 09:28:12
1445-07-4 結(jié)構(gòu)式
基本信息
中文別名
假尿苷Β-假尿苷
5-Β-D-核呋喃基尿嘧啶
Β-PSEUDOURIDINE
PSEUDOURIDINE 假尿苷
英文別名
y-UridineNSC 162405
PSEUDOURIDINE
Pseudourindine
5-Ribosyluracil
Pseudouridine C
B-Pseudouridine
β-Pseudouridine
β-D-Pseudouridine
BETA-PSEUDOURIDINE
所屬類別
生物化工：核苷類藥物物理化學(xué)性質(zhì)
熔點(diǎn)222 °C
密度1.641±0.06 g/cm3(Predicted)
儲(chǔ)存條件Inert atmosphere,Room Temperature
溶解度甲醇（微溶，加熱），水（微溶，超聲處理，加熱）
酸度系數(shù)(pKa)8.52±0.10(Predicted)
形態(tài)固體
顏色白色至灰白色
PH值～9.0
生物來(lái)源synthetic (chemical)
水溶解性water: soluble
最大波長(zhǎng)(λmax)264nm(MeOH)(lit.)
InChIInChI=1/C9H12N2O6/c12-2-4-5(13)6(14)7(17-4)3-1-10-9(16)11-8(3)15/h1,4-7,12-14H,2H2,(H2,10,11,15,16)/t4-,5-,6-,7+/s3
InChIKeyPTJWIQPHWPFNBW-IZFRNLNUNA-N
SMILESO[C@@H]1[C@@H]([C@@H](CO)O[C@H]1C1=CNC(=O)NC1=O)O |&1:1,2,3,7,r|
應(yīng)用領(lǐng)域
用途1
An isomer of the nucleoside uridine found in all species and in many classes of RNA except mRNA. It is formed by enzymes called 唯 synthases, which post-transcriptionally isomerize specific uridine res
idues in RNA in a process termed pseudouridylation. Studies suggest that β-Pseudouridine reduces radiation-induced chromosome aberrations in human lymphocytes.