成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

返回ChemicalBook首頁(yè)>CAS數(shù)據(jù)庫(kù)列表>138614-30-9

138614-30-9

中文名稱 艾替班特乙酸鹽
英文名稱 HOE-140
CAS 138614-30-9
分子式 C59H89N19O13S.C2H4O2
分子量 1364.59
MOL 文件 138614-30-9.mol
更新日期 2024/12/23 10:30:21
138614-30-9 結(jié)構(gòu)式 138614-30-9 結(jié)構(gòu)式

基本信息

中文別名
艾替班特乙酸鹽
艾替班特 ACETATE
醋酸艾替班特(艾替班特乙酸鹽,HOE 140)
D-精氨酸基-L-精氨酸基-L-脯氨?;?(4R)-4-羥基-L-脯氨?;腔?3-(2-噻吩基)-L-丙氨?;?L-絲氨酰-(3R)-1,2,3,4-四氫-3-異喹啉羰基-(2S,3aS,7aS)-八氫-1H-吲哚-2-羰基-L-精氨酸 乙酸鹽
英文別名
Firazyr
CS-1399
HOE 140 Acetate
lcatibant Acetate
HOE-140 (Icatibant)
HOE140
ICATIBANT
HOE 140
HOE 140 SYNTHETIC >99% SELECTIVE B2 BRAD YKIN
d-arg-l-arg-l-pro-l-hyp-gly-l-(2-thienyl)ala-l-ser-d-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-l-(2α,3β,7aβ)-octahydro-1h-indole-2-carbonyl-l-arg
Icatibant acetate, D-Arg-L-Arg-L-Pro-L-Hyp-Gly-L-(2-thienyl)Ala-L-Ser-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2α,3β,7aβ)-octahydro-1H-indole-2-carbonyl-L-Arg
(2S)-2-[[(3aS,7aS)-1-[2-[(2S)-2-[[(2S)-2-[[2-[[(4R)-1-[1-[2-[[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]-4-hydroxy-pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-thiophen-2-yl-propanoyl]amino]-3-hydroxy-propanoyl]3,4-dihydro-1H-isoquinoline-3-carbonyl]2,3,3a,4,5,6,7,7a-octahydroindole-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid
所屬類別
生物化工:激動(dòng)劑抑制劑

物理化學(xué)性質(zhì)

儲(chǔ)存條件-20°C
溶解度DMSO:65.0(Max Conc. mg/mL);47.63(Max Conc. mM)
Ethanol:0.25(Max Conc. mg/mL);0.18(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);7.33(Max Conc. mM)
形態(tài)A crystalline solid
顏色White to off-white

安全數(shù)據(jù)

WGK Germany3
艾替班特乙酸鹽價(jià)格(試劑級(jí))
報(bào)價(jià)日期產(chǎn)品編號(hào)產(chǎn)品名稱CAS號(hào)包裝價(jià)格
2024/11/08S5695艾替班特乙酸鹽
Icatibant Acetate
138614-30-92mg1204.11元
2024/11/08S5695艾替班特乙酸鹽
Icatibant Acetate
138614-30-95mg2212.24元
2024/11/08S5695Icatibant Acetate138614-30-925mg7126.16元

常見問題列表

生物活性
Icatibant Acetate是bradykinin B2受體的拮抗劑,可用于治療遺傳性血管性水腫。
靶點(diǎn)
TargetValue
bradykinin B2 receptor
()
體外研究

Icatibant (10-30 μM) potentiates angiotensin III, but not angiotensin II (contraction mediated by angiotensin AT1 receptors), and Lys-des-Arg9-bradykinin, but not des-Arg9-bradykinin (effects mediated by the bradykinin B1 receptors).

體內(nèi)研究

Icatibant (10-30 μM) potentiates angiotensin III, but not angiotensin II (contraction mediated by angiotensin AT1 receptors), and Lys-des-Arg9-bradykinin, but not des-Arg9-bradykinin (effects mediated by the bradykinin B1 receptors).

Animal Model: Female mice of the CBA/J (H-2 k ) strain.
Dosage: 0.06, 0.3, or 1.5 mg/kg.
Administration: Subcutaneous administration twice daily.
Result: The length of the large intestine was 93.6±6.8 mm with the 1.5 mg/kg dosage and 94.0±4.1 mm with the 0.3 mg/kg dosage , showing a significant preventive effect on shortening.
"138614-30-9" 相關(guān)產(chǎn)品信息
141732-76-5 83150-76-9 123-92-2 108-05-4 87-51-4 60-00-4 90779-69-4 10813-74-8 77591-33-4 34973-08-5 47931-85-1