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1354900-66-5

中文名稱 卡巴他賽N-1
英文名稱 Cabazitaxel N-1
CAS 1354900-66-5
分子式 C53H63NO15
分子量 954.07
MOL 文件 1354900-66-5.mol
1354900-66-5 結(jié)構(gòu)式 1354900-66-5 結(jié)構(gòu)式

基本信息

中文別名
(N-1)卡巴他賽中間體
(4S,5R)-2-(4-甲氧基苯基)-4-苯基-3,5-惡唑烷二甲酸 5-[(2AR,4S,4AS,6R,9S,11S,12S,12AR,12BS)-12B-(乙酰氧基)-12-(苯甲酰氧基)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-十二氫-11-羥基-4,6-二甲氧基-4A,8,13,13-四甲基-5-氧代-7,11-甲橋-1H-環(huán)癸五烯并[3,4]苯并[1,2-B]氧雜環(huán)丁烯-9-基] 3-叔丁基酯
英文別名
Cabazitaxel N-1
(N-1)Cabazitaxel intermediate
4α-acetoxy-2α-benzoyloxy-5β,20-epoxy-1β,13α-dihydroxy-7β,10β-dimethoxy-9-oxo-11-taxen-13α-yl (2R,4S,5S)-3-tert-butoxycarbonyl-2-(4-methoxyphenyl)-4-phenyl-1,3-oxazolidine-5-carboxylate
3,5-Oxazolidinedicarboxylic acid, 2-(4-methoxyphenyl)-4-phenyl-, 5-[(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl] 3-(1,1-dimet...
(4S,5R)-2-(4-Methoxyphenyl)-4-phenyl-3,5-oxazolidinedicarboxylic acid 5-[(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl] 3-(1,1-dimethylethyl) ester

應(yīng)用領(lǐng)域

用途一
Cabazitaxel N-1 is an impurity of Cabazitaxel (C046500), a novel semi-synthetic taxane with antitumor activity used for the treatment of castration-resistant prostate cancer.
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