114311-32-9
114311-32-9 結(jié)構(gòu)式
基本信息
甲氧咪草煙
(RS)-2-(4-異丙基-4-甲基-5-氧-2-咪唑啉-2-基)-5-甲氧基甲基尼古丁酸
金豆
(RS)-2-(4-異丙基-4-甲基-5-氧代-2-咪唑啉-2-基)-5-甲氧甲基吡啶-3-羧酸
IMAZAMOX
(RS)-2-(4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)-5-methoxymethylnicotinic acid
Odyseey
Raptor
Sweeper
Imazamox PESTANAL
AC299263
2-(4,5-Dihydro-4-methyl-4-(1-methylethyl)-5-oxo-1H-imidazol-2-yl)-5-(methoxymethyl)-3-pyridinecarboxylic acid
2-(4-Isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)-5-methoxymethylnicotinic acid, 2-[4,5-Dihydro-4-methyl-4-(1-methylethyl)-5-oxo-1H-imidazol-2-yl]-5-(methoxymethyl)-3-pyridinecarboxylic acid
CL 299263
物理化學(xué)性質(zhì)
安全數(shù)據(jù)
應(yīng)用領(lǐng)域
制備方法
以丙醛為起始原料，與甲醛縮合、閉環(huán)、鹵化、甲氧基化等一系列反應(yīng)制得甲氧咪草煙。
制備方法二
以甲氧基丙醛、草酸二乙酯、甲基異丙基酮為起始原料，經(jīng)過(guò)下述一系列反應(yīng)制得甲氧咪草煙。
常見問(wèn)題列表
后茬作物的安全性：甲氧咪草煙是咪唑咻酮類除草劑中短殘留品種，施藥后土壤中的藥劑絕大部分分解失效，因而對(duì)絕大多數(shù)后茬作物安全，在一年一熟地區(qū)的輪作中，不會(huì)傷害后茬作物，但當(dāng)混作、間種及復(fù)種時(shí)，則需考慮不同作物的敏感性及間隔時(shí)期：甲氧咪草煙以50g(a.i.)/hm2劑量使用時(shí)，種植大麥、冬小麥、春小麥所需間隔時(shí)間為4個(gè)月。種植玉米、水稻(不含苗床)、棉花、谷子、向日葵、煙草、馬鈴薯、西瓜所需間隔時(shí)間為12個(gè)月。種植油菜、甜菜所需間隔時(shí)間為18個(gè)月。
Half-life of Imazamox in the soil ranges from 1 to 3 months exhibit low mammalian toxicity. Plants are treated with Imazamox (250 μM) in the nutrient solution and harvested 7 days after. Imazamox is mainly accumulated in V. sativa , six fold higher than those detected in P.vulgaris .
Imazamox (12-36?mg/kg; intraperitoneal injection; for 24-72 hours; male Sprague-Dawley rats) treatment induces toxic effects in the liver and pancreas of Sprague Dawley rats. Necrotic and degenerative changes are detected in hepatocytes at the two highest doses. Imazamox treatment reduces the size of the β-islet cells, and also induces an elevation in serum glucose and calcium.
| Animal Model: | 50 male Sprague-Dawley rats (300?±?10?g) |
| Dosage: | 12 mg/kg, 24 mg/kg and 36?mg/kg |
| Administration: | Intraperitoneal injection; for 24 hours, 48 hours or 72 hours |
| Result: | Induced toxic effects in the liver and pancreas. |