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ChemicalBook--->CAS DataBase List--->98106-17-3

98106-17-3

98106-17-3 Structure

98106-17-3 Structure
IdentificationMore
[Name]

Difloxacin
[CAS]

98106-17-3
[Synonyms]

DIFLOXACIN
-1-piperazinyl)-4-oxo-
3-quinolinecarboxylicacid,1,4-dihydro-6-fluoro-1-(4-fluorophenyl)-7-(4-methyl
a56619
6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Hydrochloride Salt
Difloxacin Hydrochloride Salt
6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
DIFLOXACINHCL/MESYLATE
6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methylpiperazin-1-yl)-4-oxo-3-quinolinecarboxylic acid
6-Fluoro-1-(4-fluorophenyl)-7-(4-methyl-1-piperazinyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
[Molecular Formula]

C21H19F2N3O3
[MDL Number]

MFCD00865975
[Molecular Weight]

399.39
[MOL File]

98106-17-3.mol
Questions And AnswerBack Directory
[Description]

Difloxacin (INN) is a second-generation, synthetic fluoroquinolone antibiotic used in veterinary medicine,it has broad-spectrum, concentration dependent, bactericidal activity; however, its efficacy is not as good as enrofloxacin or pradofloxacin.
[Mechanism of action]

Difloxacin mainly acts on bacterial deoxyribonucleic acid (DNA) helicase, inhibiting DNA replication and transcription, thereby affecting the normal shape and function of DNA to achieve bactericidal purposes. 
Chemical PropertiesBack Directory
[Appearance]

Whtie-Cream to Yellowish Crystalline Powder
[Melting point ]

279-282 °C(Solv: chloroform (67-66-3); ethanol (64-17-5))
[Boiling point ]

595.5±50.0 °C(Predicted)
[density ]

1.409±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

DMSO (Slightly), Methanol (Slightly), Water (Slightly)
[form ]

Solid
[pka]

6.17±0.41(Predicted)
[color ]

White to Pale Yellow
[Usage]

A fluoroquinolone antibacterial structurally related to norfloxacin
[CAS DataBase Reference]

98106-17-3(CAS DataBase Reference)
Hazard InformationBack Directory
[Physical properties]

Whtie-Cream to Yellowish Crystalline Powder
[Uses]

Difloxacin is a fluoroquinolone antibacterial structurally related to norfloxacin.
[Definition]

ChEBI: A quinolone that is pefloxacin in which the ethyl group at position 1 of the quinolone has been replaced by a p-fluorophenyl group. A broad-spectrum antibiotic effective against both Gram-positive and Gram-negative bacteria, it is used (usuall as the monohydrochloride salt) for the treatment of bacterial infections in dogs.
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