| Identification | More | [Name]
p-Terphenyl | [CAS]
92-94-4 | [Synonyms]
[1,1':4',1'']TERPHENYL
4-PHENYLBIPHENYL
P-DIPHENYLBENZENE
P-TERPHENYL
PTP
TERPHENYL, P-
[1,1'
1,1'-Biphenyl, 4-phenyl-
1,4-terphenyl
4',1'']-Terphenyl
4-phenyl-1’-biphenyl
4-phenyl-bipheny
4-Phenyldiphenyl
benzene,1,4-diphenyl-
Biphenyl, 4-phenyl-
biphenyl,4-phenyl
diphenyl-1,4benzene
para-terphenyl
p-terphenyle
p-Triphenyl | [EINECS(EC#)]
202-205-2 | [Molecular Formula]
C18H14 | [MDL Number]
MFCD00003061 | [Molecular Weight]
230.3 | [MOL File]
92-94-4.mol |
| Chemical Properties | Back Directory | [Appearance]
White solid | [Melting point ]
212-213 °C(lit.)
| [Boiling point ]
389 °C(lit.)
| [density ]
1.23 | [vapor density ]
7.95 (vs air)
| [refractive index ]
1.5500 (estimate) | [Fp ]
207 °C
| [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly), DMSO (Slightly, Heated, Sonicated) | [form ]
Crystals or Crystalline Powder | [color ]
White to slightly beige | [Stability:]
Stable. Combustible. Incompatible with strong oxidizing agents. | [Water Solubility ]
practically insoluble | [λmax]
276nm(Cyclohexane)(lit.) | [Detection Methods]
HPLC,NMR | [BRN ]
1908447 | [Exposure limits]
NIOSH: IDLH 500 mg/m3; Ceiling 0.5 ppm(5 mg/m3) | [InChIKey]
XJKSTNDFUHDPQJ-UHFFFAOYSA-N | [CAS DataBase Reference]
92-94-4(CAS DataBase Reference) | [NIST Chemistry Reference]
p-Terphenyl(92-94-4) | [EPA Substance Registry System]
92-94-4(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R37/38:Irritating to respiratory system and skin .
R36:Irritating to the eyes.
R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37:Wear suitable gloves .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S60:This material and/or its container must be disposed of as hazardous waste . | [OEL]
Ceiling: 5 mg/m3 (0.5 ppm) | [RIDADR ]
UN 3077 9/PG 3 | [WGK Germany ]
2
| [RTECS ]
WZ6475000
| [TSCA ]
Yes | [HS Code ]
29029090 | [Safety Profile]
Moderately toxic by ingestion. Combustible when exposed to heat or flame. To fight fire, use water, CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes. | [Hazardous Substances Data]
92-94-4(Hazardous Substances Data) |
| Hazard Information | Back Directory | [Description]
p-Terphenyl(PTP) is an aromatic hydrocarbon isomer, formed by three benzene rings in ortho position. Pure terphenyl is a white crystalline solid, insoluble in water. Though polychlorinated terphenyls were used as heat storage and transfer agents, p-terphenyl is currently under investigation as a material to be used in opto-electronic devices, such as organic LED devices (OLEDs) and currently used in laser dyes and sunscreen lotions. In particle physics it has been used as a wavelength shifter, exploiting its sensitivity to VUV radiation, to read out scintillation light from liquid Xenon. Pterphenyl has also been used as a doping component for liquid scintillators.
So far, p-terphenyl has not been used as main component of particle detectors due to its short Light Attenuation Length. As a matter of fact this property could be exploited when detecting low-energy charged particles in small areas, providing both energy and position measurement. | [Chemical Properties]
a White or light-yellow solid. The melting point is 213°C, boiling point is 383°C, 250°C (6kPa), flash point is 207°C, and relative density is 1.234 (0°C). Soluble in hot benzene, slightly soluble in ether and carbon disulfide, extremely insoluble in ethanol and acetic acid. 427℃ sublimation. p-Terphenyl can be separated from the by-products of biphenyl production. | [Uses]
p-Terphenyl is a specialty material, and may be used in ionized radiation detectors, nonpolar laser dye, and single molecule optical probe of scanning near-field microscopy. | [Application]
LCD Electronics: P-Terphenyl is one of the basic intermediates for preparing diphenyl LCD materials at present.
Organic synthesis: P-Terphenyl is the basic raw material for synthesizing antifungal cyclic peptide (4-carboxyl P–Terphenyl CTP) and diphenyl polyamide material 4, 4-（DCTP).
Fine chemical engineering: under radiation, P-Terphenyl will generate fluorescence, and thus it can be used as an organic scintillation reagent. It is used as an illuminant in scintillation counters and as a synthetic intermediate for laser dyes.
p-Terphenyl-Sensitized Photoreduction of CO2 with Cobalt and Iron Porphyrins. Interaction between CO and Reduced Metalloporphyrins | [Definition]
ChEBI: p-Terphenyl is a para-terphenyl that consists of benzene attached to two phenyl units at positions 1 and 4 respectively. | [Synthesis Reference(s)]
Chemical and Pharmaceutical Bulletin, 30, p. 802, 1982 DOI: 10.1248/cpb.30.802
The Journal of Organic Chemistry, 50, p. 3104, 1985 DOI: 10.1021/jo00217a018 | [General Description]
White or light-yellow needles or leaves. Mp: 212-213°C; bp 376°C. Density: 1.23 g cm-3. Insoluble in water. Soluble in hot benzene. Very soluble in hot ethyl alcohol. Usually shipped as a solid mixture with its isomers o-terphenyl and m-terphenyl that is used as a heat-transfer fluid. | [Reactivity Profile]
p-Terphenyl(92-94-4) is non-flammable but combustible (flash point: 410°C). Extremely stable thermally. Incompatible with strong oxidizing agents but not very reactive at room conditions. | [Hazard]
Toxic by ingestion and inhalation. Eye and
upper respiratory tract irritant. | [Purification Methods]
Crystallise p-terphenyl from nitrobenzene or trichlorobenzene. It is also purified by chromatography on alumina in a darkened room, using pet ether, and then crystallising from pet ether (b 40-60o) or pet ether/*benzene. It is a fluorophore for scintillation counting and has ex 286nm : em 343nm in DMF, and max 277nm (log 4.50). [Beilstein 5 IV 2483.] | [Structure and conformation]
The most prominent character in the structure of p-terphenyl is that they possess an aromatic or a para quinone group in the central ring, which, in nearly all cases, carries additional oxygen functions as well. The structural diversity resulted from the variation of the ring B and the connections between the rings, and to the main skeleton, one or more oxygen functions like hydroxy group, methoxy group or ester group at C-3′, C-4′, C-4′′, or/and C-5′′ were attached. The UV spectrum of p-terphenyls showed absorption maxima at 260–300 nm and more than 300 nm indicating the presence of conjugated or aromatic systems. Their IR spectrum mostly has absorption bands of phenolic hydroxyl (3200–3500 cm-1) and benzene groups (about 1600 and about 1500 cm-1)[1].
| [References]
[1] Zhou, Guoliang , et al. "Structural diversity and biological activity of natural p-terphenyls." Journal of Asian Natural Products Research4.1(2022):12.
[2] Takahashi, S , et al. "Total Synthesis of Kehokorins A–E, Cytotoxic p-Terphenyls."Journal of Organic Chemistry82.6(2017):3159. |
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