| Identification | More | [Name]
1,2-Bis(bromomethyl)benzene | [CAS]
91-13-4 | [Synonyms]
1,2-BIS(BROMOMETHYL)BENZENE
A,A'-DIBROMO-O-XYLENE
ALPHA,ALPHA'-DIBROMO-2-XYLENE
ALPHA,ALPHA'-DIBROMO-O-XYLENE
ALPHA,ALPHA-DIBROMO-O-XYLENE
O-XYLENE DIBROMIDE
O-XYLIDENE DIBROMIDE
O-XYLYLENE BROMIDE
O-XYLYLENE DIBROMIDE
1,2-bis(bromomethyl)-benzen
alpha,alpha '-Dibromo-ortho-xylene
alpha,alpha'-Dibromo-o-xylol
benzene,1,2-bis(bromomethyl)-
o-(Bromomethyl)benzyl bromide
o-Bis(bromomethyl)benzene
o-Xylene, alpha,alpha'-dibromo-
α,α’-dibromo-o-xylene
1,2-Bis(bromomethyl)benzene~alpha,alpha-Dibromo-o-xylene
O-XYLYLENE DIBROMIDE 97%
o-Xylylenedibromide,97% | [EINECS(EC#)]
202-042-7 | [Molecular Formula]
C8H8Br2 | [MDL Number]
MFCD00000175 | [Molecular Weight]
263.96 | [MOL File]
91-13-4.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powde | [Melting point ]
91-94 °C(lit.) | [Boiling point ]
140 °C / 20mmHg | [density ]
1.96 g/mL at 25 °C(lit.)
| [refractive index ]
1.6113 (estimate) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
sol ethanol, ether, chloroform; slightly sol petroleum ether. | [form ]
Crystals or Crystalline Powder | [color ]
White to light cream | [Water Solubility ]
soluble, hydrolyses | [Detection Methods]
GC,NMR | [BRN ]
637159 | [InChIKey]
KGKAYWMGPDWLQZ-UHFFFAOYSA-N | [CAS DataBase Reference]
91-13-4(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzene, 1,2-bis(bromomethyl)-(91-13-4) | [Storage Precautions]
Moisture sensitive;Light sensitive | [EPA Substance Registry System]
91-13-4(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R22:Harmful if swallowed.
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 3448 6.1/PG 2
| [WGK Germany ]
2
| [F ]
8-19-21 | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29036990 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powde | [Uses]
1,2-Bis(bromomethyl)benzene is used in the synthesis of isothioureas involved in the inhibition of human nitric oxide synthases. Also used in the synthesis of tridentate carbene ligands. | [Application]
1,2-Bis(bromomethyl)benzene (α,α′-Dibromo-o-xylene) is a source of o-quinodimethane, a highly reactive diene useful in Diels-Alder reactions; an electrophile for
the synthesis of carbo- and heterocyclic compounds including macrocycles (cyclophanes, crown ethers,
hemispherands, spherands), cryptands, hemicarcerands, vaulted cappedophanes, bicyclic compounds,
spirocyclic compounds; a protective group reagent for diols. | [storage]
1,2-Bis(bromomethyl)benzene should be avoided moisture; corrosive (forms HBr on hydrolysis); lachrymator;
not mutagenic in Ames test; decontaminate by soaking apparatus, etc. in alcoholic alkali for 24 h or longer. | [Purification Methods]
Crystallise it from CHCl3 or pet ether, and/or distil it under vacuum. [Wenner Org Chem 17 527 1952, Beilstein 5 H 366, 5 I 180, 5 II 285, 5 III 819, 5 IV 929.] |
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