Identification | More | [Name]
Cefodizime sodium | [CAS]
86329-79-5 | [Synonyms]
7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((5-(carboxymethyl)-4-methyl-2-thiazolyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid disodium salt CEFODIZIME DISODIUM CEFODIZIME SODIUM CEFODIZIME SODIUM SALT kenicef )(methoxyimino)acetyl)amino)-3-(((5-(carboxymethyl)-4-methyl-2-thiazolyl)thio 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((5-(carboxymethyl)-4-methyl-2-thiazolyl)th5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicaci 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid disodiumsalt,(6r-(6-alpha,7-beta(z)))-)methyl)-8-oxo thr-221 Cefodizimedisodiumsalt 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-, disodium salt, [6R-[6α,7β(Z)]]- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-, disodium salt, (6R,7R)- HR 221 S 77-1221B Timecef CefodizimeSodium(Sterile) Cefodizim-Dinatriumsalz 7-[[(2-amino-4-thiazolyl) (methoxyimino) acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 7-(((2-Amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((5-(carboxymethyl)-4-methyl-2-thiazolyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid disodium salt | [Molecular Formula]
C20H18N6Na2O7S4 | [MDL Number]
MFCD00897059 | [Molecular Weight]
628.63 | [MOL File]
86329-79-5.mol |
Hazard Information | Back Directory | [Hazard]
Low toxicity by ingestion. | [Description]
Cefodizirne sodium is a parenteral, long-acting, broad-spectrum cephalosporin useful in the treatment of bacterial infections. It is efficacious against pathogens resistant to
penicillins and older cephalosporins. An indication under study is its reported
immunostimulatory activity. | [Originator]
Hoechst AG (Germany) | [Uses]
Cefodizime Sodium (cas# 86329-79-5) is a compound useful in organic synthesis. | [Definition]
ChEBI: Cefodizime sodium is a cephalosporin. | [Brand name]
Neucef; Kenicef | [Biochem/physiol Actions]
Cefodizime is a third generation cephalosporin with a broad spectrum of antibacterial activity. Cefodizime was demonstrated to be effective against upper and lower respiratory tract infections, urinary tract infections, and gonorrhea. Cefodizime regulates the cytokines expression of neutrophils through toll-like receptor 4 (TLR-4) stimulated by Klebsiella pneumonie. |
Safety Data | Back Directory | [Toxicity]
LD50 in mice, rabbits (mg/kg): 4000-8000 i.v. both species; in rats (mg/kg): 4000-8000 i.v., 15000-17500 s.c., 8000-11000 i.p. (Bryskier) |
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