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ChemicalBook--->CAS DataBase List--->86329-79-5

86329-79-5

86329-79-5 Structure

86329-79-5 Structure
IdentificationMore
[Name]

Cefodizime sodium
[CAS]

86329-79-5
[Synonyms]

7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((5-(carboxymethyl)-4-methyl-2-thiazolyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid disodium salt
CEFODIZIME DISODIUM
CEFODIZIME SODIUM
CEFODIZIME SODIUM SALT
kenicef
)(methoxyimino)acetyl)amino)-3-(((5-(carboxymethyl)-4-methyl-2-thiazolyl)thio
7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((5-(carboxymethyl)-4-methyl-2-thiazolyl)th5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicaci
7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid
disodiumsalt,(6r-(6-alpha,7-beta(z)))-)methyl)-8-oxo
thr-221
Cefodizimedisodiumsalt
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-, disodium salt, [6R-[6α,7β(Z)]]-
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-, disodium salt, (6R,7R)-
HR 221
S 77-1221B
Timecef
CefodizimeSodium(Sterile)
Cefodizim-Dinatriumsalz
7-[[(2-amino-4-thiazolyl) (methoxyimino) acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
7-(((2-Amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((5-(carboxymethyl)-4-methyl-2-thiazolyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid disodium salt
[Molecular Formula]

C20H18N6Na2O7S4
[MDL Number]

MFCD00897059
[Molecular Weight]

628.63
[MOL File]

86329-79-5.mol
Chemical PropertiesBack Directory
[Melting point ]

196 - 207°C
[storage temp. ]

2-8°C
[solubility ]

DMSO (Slightly), Methanol (Sparingly)
[form ]

powder
[color ]

White to Off-White
[Stability:]

Hygroscopic
[CAS DataBase Reference]

86329-79-5(CAS DataBase Reference)
Hazard InformationBack Directory
[Hazard]

Low toxicity by ingestion.
[Description]

Cefodizirne sodium is a parenteral, long-acting, broad-spectrum cephalosporin useful in the treatment of bacterial infections. It is efficacious against pathogens resistant to penicillins and older cephalosporins. An indication under study is its reported immunostimulatory activity.
[Originator]

Hoechst AG (Germany)
[Uses]

Cefodizime Sodium (cas# 86329-79-5) is a compound useful in organic synthesis.
[Definition]

ChEBI: Cefodizime sodium is a cephalosporin.
[Brand name]

Neucef; Kenicef
[Biochem/physiol Actions]

Cefodizime is a third generation cephalosporin with a broad spectrum of antibacterial activity. Cefodizime was demonstrated to be effective against upper and lower respiratory tract infections, urinary tract infections, and gonorrhea. Cefodizime regulates the cytokines expression of neutrophils through toll-like receptor 4 (TLR-4) stimulated by Klebsiella pneumonie.
Safety DataBack Directory
[Toxicity]

LD50 in mice, rabbits (mg/kg): 4000-8000 i.v. both species; in rats (mg/kg): 4000-8000 i.v., 15000-17500 s.c., 8000-11000 i.p. (Bryskier)
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