| Identification | Back Directory | [Name]
Sophoridine | [CAS]
83148-91-8 | [Synonyms]
SOPHORIDINE
I-SOPHORIDINE
MATRIDIN-15-ONE
SOPHORIDINE(RG)
(-)-SOPHORIDINE
(+)-Sophoridine
5-EPIDIHYDROSOPHOCARPINE
DIHYDRO-5-EPISOPHOCARPINE
Matridin-15-one, (6β,7β,11α)- (9CI) | [Molecular Formula]
C15H24N2O | [MDL Number]
MFCD00238686 | [MOL File]
83148-91-8.mol | [Molecular Weight]
248.36 |
| Chemical Properties | Back Directory | [Melting point ]
108-9°C | [Boiling point ]
396.7±31.0 °C(Predicted) | [density ]
1.16±0.1 g/cm3(Predicted) | [solubility ]
Chloroform (Slightly), Methanol (Slightly), Water (Slightly) | [form ]
Solid | [pka]
9.47±0.20(Predicted) | [color ]
Pale Yellow | [CAS DataBase Reference]
83148-91-8 |
| Hazard Information | Back Directory | [Description]
One of a number of minor alkaloids isolated from Leontice albertii Rgl., this
base crystallizes from petroleum ether as colourless prisms. It is dextrorotatory
having a specific rotation of [α]D + 59.3° (c 1.3, EtOH) and yields a crystalline
methiodide, m.p. 249°C. The structure has been assigned on the basis of chemical
analysis and spectroscopic determinations. | [Uses]
(+)-Sophoridine acts as an anti-inflammatory agent in vitro and in vivo. Anticancer agent, with a promising anti-tumor effect and lower toxicity. | [in vivo]
Sophoridine (intraperitoneal injection; 20 or 40 mg/kg; 21 days) can inhibit the growth of xenograft pancreatic tumors[1]. | [References]
Kamalitdinov, Iskandarov, Yunusov, Khim. Prir. Soedin., 3, 352 (1967)
Kamalitdinov, Iskandarov, Yunusov, ibid, 5,409 (1969) |
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