Identification | Back Directory | [Name]
Erythromycin ethylsuccinate | [CAS]
1264-62-6 | [Synonyms]
Esinol Evesin Refkas Anamycin Arpimycin E-Mycin e Eryliquid Sigapedil Monomycin Wyamycin E Erythro ES erythroped Durapaediat Erythro-Holz Paediathrocin Erythromycin ethyl s erythrocinethylsuccinate ErythroMycin ethyl succina ERYTHROMYCIN ETHYLSUCCINATE ERYTHROMYCIN ETHLY SUCCINATE. ERYTHROMYCINETHYLSUCCINATE,USP ErythroMycin Ethylsuccinate API ERYTHROMYCIN ETHYISUCCINATE USP erythromycin,mono(ethylsuccinate) ERYTHROMYCIN 2'-(ETHYL SUCCINATE) Erythromycin ethyl succinate (6CI) ERYTHROMYCIN 2'-(ETHYL BUTANEDIOATE) Erythromycin Ethylsuccinate (200 mg) Oxacyclotetradecane, erythromycin deriv. erythromycin,mono(ethylsuccinate)(ester) Erythromycin, 2'-(ethyl succinate) (7CI) Succinic acid, monoester with erythromycin ERYTHROMYCIN ETHYLSUCCINATE EPE(CRM STANDARD) ERYTHROMYCIN ETHYLSUCCINATE USP(CRM STANDARD) Erythromycin 2''-[3-(ethoxycarbonyl)propionate] Erythromycin, mono(ethyl succinate) (ester) (8CI) succinicacid,monoethylester,monoesterwitherythromycin Succinic acid, ethyl ester, monoester with erythromycin (8CI) Ethyl [(2R,3S,4R,6S)-4-dimethylamino-2-[[(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-14-ethyl-7,12,13-trihydroxy-4-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyl-oxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-1-oxacyclotetradec-6-yl]oxy]-6-methyl-oxan-3-yl] butanedioate | [EINECS(EC#)]
215-033-8 | [Molecular Formula]
C43H75NO16 | [MDL Number]
MFCD00084692 | [MOL File]
1264-62-6.mol | [Molecular Weight]
862.05 |
Chemical Properties | Back Directory | [Melting point ]
219-224 C | [Boiling point ]
778.19°C (rough estimate) | [density ]
1.1417 (rough estimate) | [refractive index ]
1.5280 (estimate) | [Fp ]
>110°(230°F) | [storage temp. ]
2-8°C | [solubility ]
ethanol: soluble50mg/mL | [form ]
solid | [pka]
13.09±0.70(Predicted) | [color ]
white | [Water Solubility ]
Freely soluble in organic solvents, practically insoluble in water | [Stability:]
Hygroscopic | [CAS DataBase Reference]
1264-62-6 |
Hazard Information | Back Directory | [Chemical Properties]
crystals | [Uses]
antibacterial | [Brand name]
E-Mycin (Pharmacia & Upjohn); E.E.S.
(Abbott); Eryped (Abbott); Pediamycin (Ross); Wyamycin
(Wyeth). | [Definition]
ChEBI: Erythromycin ethylsuccinate is a erythromycin derivative that is erythromycin A in which the hydroxy group at position 3R is substituted by a (4-ethoxy-4-oxobutanoyl)oxy group. It is used for the treatment of a wide variety of bacterial infections. It is a succinate ester, a cyclic ketone, an erythromycin derivative and an ethyl ester. It is functionally related to an erythromycin A. | [General Description]
Erythromycin ethylsuccinate (EES, Pediamycin, EryPed) isthe ethylsuccinate mixed ester of erythromycin in which the2'-hydroxyl group of the desosamine is esterified. It isabsorbed as the ester and hydrolyzed slowly in the body toform erythromycin. It is somewhat acid labile, and itsabsorption is enhanced by the presence of food. The ester isinsoluble in water but soluble in alcohol and ether. | [storage]
Store at -20°C |
|
|