| Identification | More | [Name]
1,8-DICHLOROANTHRAQUINONE | [CAS]
82-43-9 | [Synonyms]
1,8-DICHLOROANTHRAQUINONE
1,8-Dichloranthrachinon
1,8-dichloro-10-anthracenedione
1,8-Dichloro-9,10-anthraquinone
1,8-Dichloroanthra-9,10-quinone
1,8-dichloro-anthraquinon
9,10-Anthracenedione, 1,8-dichloro-
1,8-Dichloroanthraquinone,97%
1,8-dichloroanthracene-9-10-dione
1,8-Dichloroanthraquinone,96%
1,8-Dichloro-9,10-anthracenedione
1,8-Dichloro-9,10-dihydroanthracene-9,10-dione
4,5-Dichloro-9,10-anthraquinone | [EINECS(EC#)]
201-420-9 | [Molecular Formula]
C14H6Cl2O2 | [MDL Number]
MFCD00001191 | [Molecular Weight]
277.1 | [MOL File]
82-43-9.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [WGK Germany ]
3
| [RTECS ]
CB6496000
| [Hazard Note ]
Irritant | [TSCA ]
Yes | [HS Code ]
2914790090 | [Safety Profile]
An eye irritant. When
heated to decomposition it emits toxic
fumes of Cl-. |
| Hazard Information | Back Directory | [Uses]
1,8-Dichloroanthraquinone is a reagent in the preparation of anthraquinones, which has antitumor activities. It is used as primary and secondary intermediate. | [Synthesis]
1,8-Dichloroanthraquinone is prepared by the reaction of 1-chloroanthracene-9,10-dione and 2-chloroanthracene-9,10-dione. The steps are as follows:
80 L of the mother liquors obtained according to Example 1a and 40 L of the mother liquors obtained according to Example 1b are combined in a 250 L enamel kettle and heated to 100℃. 12 L of a 10% strength aqueous sodium chlorate solution are fed in at a uniform rate at this temperature in the course of 4 hours, while stirring at 30 - 40 revolutions per minute with an anchor stitter. The mixture is stirred for a further 2 hours at 100℃. and filtered at 80℃. through a filter press, the material on the filter is washed with hot water until the filtrate gives a neutral reaction and the filter cake is dried. 1,8-dichloroanthraquinone are obtained.
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