| Identification | More | [Name]
2-Amino-6-fluorobenzonitrile | [CAS]
77326-36-4 | [Synonyms]
2-AMINO-6-FLUOROBENZONITRILE
2-FLUORO-6-AMINOBENZONITRILE
6-FLUOROANTHRANILONITRILE
6-AMINO-2-FLUOROBENZONITRILE
2-Amino-6-fluorobenzonitrile, 97+% (6-Fluoroanthranilonitrile)
Benzonitrile, 2-amino-6-fluoro-(9CI)
2-Amino-6-fluorobenzonitrile 98%
2-Amino-6-fluorobenzonitrile98%
2-AMINO-6-FLUOROBENZONITRILE: 98.5%
6-Fluoro-2-aminobenzonitrile | [Molecular Formula]
C7H5FN2 | [MDL Number]
MFCD00015477 | [Molecular Weight]
136.13 | [MOL File]
77326-36-4.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,T,Xn | [Risk Statements ]
R36:Irritating to the eyes.
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S22:Do not breathe dust . | [RIDADR ]
3439 | [WGK Germany ]
2
| [Hazard Note ]
Irritant | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29269090 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powder | [Uses]
2-Amino-6-fluorobenzonitrile, a medicinal chemistry intermediate, has been employed for the preparation of tacrine-related compounds. It may be used for the synthesis of antifolate and antibacterial quinazoline derivatives.
It may be used for the synthesis bis(4-oxoquinazolin-2-yl)pyridine and fluoro-containing quinazolin-4(1H)-ones. It may be employed for the synthesis of the following novel huprines:
- 12-amino-3-chloro-6,7,10,11-tetrahydro-9-isopropyl-7,11-methanocycloocta[b]quinoline hydrochloride
- 9-allyl-12-amino-3-chloro-6,7,10,11-tetrahydro-7,11-methanocycloocta[b]quinoline hydrochloride
- 12-amino-1-fluoro-6,7,10,11-tetrahydro-9-isopropyl-7,11-methanocycloocta[b]quinoline hydrochloride
- 9-allyl-12-amino-1-fluoro-6,7,10,11-tetrahydro-7,11-methanocycloocta[b]quinoline hydrochloride
| [General Description]
2-Amino-6-fluorobenzonitrile can be prepared by treatment of 2,6- difluorobenzonitrile with ammonia, which involves displacement of one of the activated fluorine atoms. |
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