| Identification | More | [Name]
4-Fluorobenzaldehyde | [CAS]
459-57-4 | [Synonyms]
4-FLUOROBENZALDEHYDE
AKOS BBS-00003166
FLUOROBENZALDEHYDE(4-)
LABOTEST-BB LT00930357
PARA FLUOROBENZALDEHYDE
PFAD
PFBA
P-FLUOROBENZALDEHYDE
4-fluoro-benzaldehyd
Benzaldehyde, p-fluoro-
p-Fluorobenzaldehyde 4-Fluorobenzaldehyde
4-Fluorobenzaldehyde,98%
Benzaldehyde, 4-fluoro-
4-Fluorobenzaldehyde99%
4-Fluorbenzaldehyd
4-FLUORO-BENZALDEHYDE 99.5%
19) PARA FLUORO BENZALDEHYDE
P-FLUORBENZALDEHYDE
p-Fluorobenzenecarboxaldehyde | [EINECS(EC#)]
207-293-6 | [Molecular Formula]
C7H5FO | [MDL Number]
MFCD00003378 | [Molecular Weight]
124.11 | [MOL File]
459-57-4.mol |
| Chemical Properties | Back Directory | [Appearance]
Clear colorless to yellow liquid | [Melting point ]
-10 °C (lit.) | [Boiling point ]
181 °C/758 mmHg (lit.) | [density ]
1.157 g/mL at 25 °C(lit.)
| [vapor pressure ]
19 hPa (70 °C) | [refractive index ]
n20/D 1.521(lit.)
| [Fp ]
134 °F
| [storage temp. ]
Store below +30°C. | [solubility ]
Chloroform, Methanol | [form ]
Liquid | [color ]
Clear colorless to yellow | [Specific Gravity]
1.157 | [Water Solubility ]
IMMISCIBLE | [Sensitive ]
Air Sensitive | [Detection Methods]
GC,NMR | [BRN ]
385857 | [Stability:]
Air Sensitive | [InChIKey]
UOQXIWFBQSVDPP-UHFFFAOYSA-N | [CAS DataBase Reference]
459-57-4(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzaldehyde, 4-fluoro-(459-57-4) | [EPA Substance Registry System]
459-57-4(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,F | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S27:Take off immediately all contaminated clothing . | [RIDADR ]
UN 1989 3/PG 3
| [WGK Germany ]
2
| [F ]
9-23 | [Hazard Note ]
Flammable | [TSCA ]
T | [HazardClass ]
3.2 | [PackingGroup ]
III | [HS Code ]
29130000 |
| Hazard Information | Back Directory | [Chemical Properties]
Clear colorless to yellow liquid | [Uses]
4-Fluorobenzaldehyde is a fluorinated benzaldehyde with inhibitory activity of mushroom tyrosinase. 4-Fluorobenzaldehyde is commonly used as a synthetic intermediate in the preparation of pharmaceutic
al compounds. | [Uses]
Usually used in the preparation of pyrazolopyridine UR-13756. | [Synthesis]
4-Fluorobenzaldehyde is produced by a commercially feasible process. The process comprises heating a mixture of fluorobenzene and a strong Lewis acid with dissolved hydrogen halide in an atmosphere of carbon monoxide at about 45 to about 100° C. and at a total pressure of about 150 psig up to the maximum pressure rating of the reactor. Formed is a reaction mass containing a Lewis acid complex of 4-fluorobenzaldehyde and at least a halobis(fluorophenyl)methane by-product. The complex is broken by quenching the reaction mass with a Lewis acid-solvating liquid to liberate 4-fluorobenzaldehyde. By-product halobis(fluorophenyl)methane is converted to di(fluorophenyl)methanol to avoid potential corrosion problems and formation of light-sensitive color bodies in the recovered 4-fluorobenzaldehyde.
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