| Identification | Back Directory | [Name]
Morachalcone A | [CAS]
76472-88-3 | [Synonyms]
Morachalcone A
(2E)-1-[2,4-Dihydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(2,4-dihydroxyphenyl)-2-propen-1-one
2-Propen-1-one, 1-[2,4-dihydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(2,4-dihydroxyphenyl)-, (2E)- | [Molecular Formula]
C20H20O5 | [MDL Number]
MFCD20274600 | [MOL File]
76472-88-3.mol | [Molecular Weight]
340.37 |
| Hazard Information | Back Directory | [Description]
Morachalcone A exhibits neuroprotective effects on HT22-immortalized hippocampal cells against glutamate-induced oxidative stress, with EC50 values of 35.5±1 uM.
Morachalcone A exhibits potent inhibitory activity on nitric oxide production in RAW264.7 LPS-activated mouse macrophage cells with IC50 value of 16.4 microM.
3. Morachalcone A displays significant tyrosinase inhibitory activity (IC50, 0.013 uM).
4. Morachalcone A exerts strong pancreatic lipase inhibition with IC 50 value of 6.2 uM. | [Definition]
ChEBI: Morachalcone A is a member of chalcones. | [target]
Tyrosinase | NO |
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