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ChemicalBook--->CAS DataBase List--->33457-62-4

33457-62-4

33457-62-4 Structure

33457-62-4 Structure
IdentificationBack Directory
[Name]

(4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one
[CAS]

33457-62-4
[Synonyms]

Alnustone
Alnvstone
(4E,6E)-1,7-diphenylhepta-4,6-dien-3-one
(4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one
4,6-Heptadien-3-one, 1,7-diphenyl-, (4E,6E)-
[Molecular Formula]

C19H18O
[MDL Number]

MFCD00926095
[MOL File]

33457-62-4.mol
[Molecular Weight]

262.35
Chemical PropertiesBack Directory
[Melting point ]

60.5-61℃
[Boiling point ]

442.9±34.0 °C(Predicted)
[density ]

1.058±0.06 g/cm3 (20 ºC 760 Torr)
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

Soluble in DMSO and methanol;
[form ]

Powder
[color ]

White to yellow
[Water Solubility ]

insoluble in water
[Stability:]

Light Sensitive
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
[HS Code ]

29143990
Hazard InformationBack Directory
[Uses]

Alnustone is a naturally occuring compound that is found in the rhizomes of Curcuma xanthorrhiza, a plant used in Indonesian folk medicine for its analgesic effects. Alnustone exhibits anti-inflammatory, antihepatotoxic and antiemetic activities.
[Definition]

ChEBI: Alnustone is a diarylheptanoid.
[Biological Activity]

Alnustone is a diarylheptanoid isolated from Alpinia katsumadai Hayatarhizomes of Curcuma xanthorrhiza and other plants th at exhibits anti-hyperglycemicanti-inflammatoryantihepatotoxic and antiemetic activities. Alnustone is a potent inhibitor of the Thyroid Adenoma Associated (THADA) functionwhich reverses THADA-induced β-cell dysfunction and ameliorate hyperglycemia in obese mice. It significantly decreases fed blood glucose and improved glucose tolerance in mice.
[target]

Immunology & Inflammation related
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