| Identification | More | [Name]
2,3,5-Trifluoropyridine | [CAS]
76469-41-5 | [Synonyms]
2,3,5-TRIFLUOROPYRIDINE
2,3,5-Trifluoropyridine 98%
2,3,5-Trifluoropyridine98% | [EINECS(EC#)]
680-886-9 | [Molecular Formula]
C5H2F3N | [MDL Number]
MFCD03001162 | [Molecular Weight]
133.07 | [MOL File]
76469-41-5.mol |
| Chemical Properties | Back Directory | [Appearance]
Colorless liquid | [Boiling point ]
102°C | [density ]
1,499 g/cm3 | [refractive index ]
1.422 | [Fp ]
30°C | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [pka]
-5.28±0.20(Predicted) | [Specific Gravity]
1.499 | [Water Solubility ]
Difficult to mix in water. | [BRN ]
6385503 | [CAS DataBase Reference]
76469-41-5(CAS DataBase Reference) |
| Questions And Answer | Back Directory | [Synthesis]
A solution of pentafluoropyridine (3) (0.6 g, 3.6 mmol) in tetrahydrofuran (5 cm3) was added to a mixture of lithium aluminium hydride (5 cm3, 5 mmol of 1.0 M solution in ether) and 12-crown-4 (1.0 g, 5.7 mmol) in THF (10 cm3) at 0 "C, with stirring, under an atmosphere of dry nitrogen. The mixture was stirred at 0 "C for 10 min, then at room temperature for 19 h, then iced water added and the mixture extracted into ether. The ether solution was dried (MgS04), evaporated and the products were isolated by preparative scale GLC (1 0% SE, 40"C), giving 2,3,5-trifluoropyridine (7, 92%) 50(Found: C, 44.9; H, 1.3; N, 10.5. Calc. for C5H2F3N: C, 45.1; H, 1.5; N, 10.5); IR spectrum no. 2; mass spectrum no. 3; nmr spectrum no. 3. |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,F,C | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R10:Flammable. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S37:Wear suitable gloves . | [RIDADR ]
1993 | [Hazard Note ]
Flammable/Irritant | [HazardClass ]
3 | [PackingGroup ]
III | [HS Code ]
29333990 |
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