| Identification | Back Directory | [Name]
(-)-TEPHROSIN | [CAS]
76-80-2 | [Synonyms]
Isotephrosin
Deguelinol I
Hydroxydeguelin
Tephrosin (synthetic)
(-)-TEPHROSIN USP/EP/BP
Tephrosin >=95% (LC/MS-ELSD)
13,13a-Dihydro-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7(7aH)-one
3H-Bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7- (7aH)-one,13,13a-dihydro-7a-hydroxy-9,10- dimethoxy-3,3-dimethyl-,(7aR,13aR)- | [Molecular Formula]
C23H22O7 | [MDL Number]
MFCD00238693 | [MOL File]
76-80-2.mol | [Molecular Weight]
410.42 |
| Chemical Properties | Back Directory | [Melting point ]
198° (218-220°) | [Boiling point ]
450.42°C (rough estimate) | [density ]
1.2284 (rough estimate) | [refractive index ]
1.5300 (estimate) | [storage temp. ]
-20°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Cryst. | [pka]
10.47±0.40(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Tephrosin as a natural rotenoid obtained from Tephrosia vogelii and displays anticancer activity. | [Definition]
ChEBI: A member of the class of rotenones that is 13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one substituted with geminal methyl groups at position 3, hydroxy group at position 7a a
d methoxy groups at positions 9 and 10 (the 7aR,13aR stereoisomer). It is isolated from the leaves and twigs of Antheroporum pierrei and exhibits antineoplastic and pesticidal activities. | [target]
ROS | PARP | Autophagy | HSP (e.g. HSP90) | EGFR | Akt | ERK | Caspase | AMPK | mTOR |
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BioBioPha Co., Ltd.
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0871-65217109 13211707573; |
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http://www.biobiopha.com |
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