| Identification | More | [Name]
TRANS-11-OCTADECENOIC ACID | [CAS]
693-72-1 | [Synonyms]
11-OCTADECENOIC ACID
11-OCTADECENOIC ACID (TRANS)
11-TRANS-OCTADECENOIC ACID
DELTA 11 TRANS OCTADECENOIC ACID
TRANS-11-OCTADECENOIC ACID
TRANS-11-OLEIC ACID
TRANS-VACCENIC ACID
VACCENIC ACID
VACCENIC ACID (TRANS)
(e)-11-octadecenoicaci
11-Octadecenoic acid, (E)-
(E)-octadec-11-enoic acid
trans-11-Octadecenoicacid,mixtureoftrans-11-and
(E)-octadec-10-enoic acid
TRANS-18:1FATTYACIDS
11-TRANSVACCENICACID
TRANS18:1ACIDS
18:1TRANSFATTYACID
TRANS-11-VACCENICACID
(E)-Octadec-11-ensure | [EINECS(EC#)]
211-758-9 | [Molecular Formula]
C18H34O2 | [MDL Number]
MFCD00002734 | [Molecular Weight]
282.46 | [MOL File]
693-72-1.mol |
| Chemical Properties | Back Directory | [Melting point ]
44℃ | [Boiling point ]
397.91°C (estimate) | [density ]
0.8563 | [refractive index ]
1.4472 (589.3 nm 50℃) | [Fp ]
113 °C | [storage temp. ]
−20°C
| [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | [form ]
Liquid | [pka]
4.78±0.10(Predicted) | [color ]
Clear Colourless | [biological source]
synthetic (organic) | [Merck ]
13,9965 | [CAS DataBase Reference]
693-72-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
1
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| Hazard Information | Back Directory | [Uses]
Vaccenic Acid is a fatty acid found in Artemia salina that shows antimicrobial activity against a variety of microorganisms except Escherichia coli, Micrococcus luteus and Salmonella enteritidis. | [Definition]
ChEBI: Vaccenic acid is an octadecenoic acid having a double bond at position 11; and which can occur in cis- or trans- configurations. It is an octadecenoic acid and a straight-chain fatty acid. It is a conjugate acid of a vaccenate(1-). | [in vivo]
trans-Vaccenic acid (1% w/w; diet; for 8 weeks) alleviates features of metabolic syndrome (MetS) potentially by remodeling adipose tissue and attenuating ectopic lipid accumulation in a rat model of obesity and MetS[3]. | Animal Model: | Obese JCR:LA-cp rats[3]. | | Dosage: | 1% w/w | | Administration: | Diet; for 8 weeks | | Result: | Reduced total body fat and decreased adipocyte size.
Increased metabolic rate concomitantly with an increased preference for whole-body glucose utilization for oxidation and increased insulin sensitivity.
Decreased nonalcoholic fatty liver disease activity scores and reduced hepatic and intestinal triglyceride secretion, while exerting differential transcriptional regulation of SREBP1 and FAS amongst other key genes in the liver and the intestine. |
| [IC 50]
Human Endogenous Metabolite | [Purification Methods]
Crystallise the acid from acetone (m 45-45.5o) or aqueous MeOH (m 43.5-43.7o). The methyl ester has b 174-175o/5mm. [B.eseken & Hoagland Rec Trav Chim, Pays Bas 46 632 1927, Ahmad et al. J Am Chem Soc 70 3391 1948, IR: Rao & Daubert J Am Chem Soc 70 1102 1948.] |
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| Company Name: |
Spectrum Chemical Manufacturing Corp.
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| Tel: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
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