| Identification | More | [Name]
7-Methoxy-1-tetralone | [CAS]
6836-19-7 | [Synonyms]
1(2H)-NAPHTHALENONE, 3,4-DIHYDRO-7-METHOXY-
7-METHOXY-1-TETRALONE
7-METHOXY-3,4-DIHYDRO-2H-NAPHTHALEN-1-ONE
7-Methoxy-3,4-dihydro-1(2H)-naphthalenone
7-methoxy-1,2,3,4-tetrahydronaphthalen-1-one
7-Methoxy-1-tetralone/CH79635
7-Methoxy-1-tetralone,99%
7-Methoxy-1-oxo-tetralin
7-METHOXY-1-TETRALONE,99.5+%
7-METHOXY-TETRALONE
1,2,3,4-Tetrahydro-7-methoxynaphthalen-1-one
7-Methoxy-1,2,3,4-tetrahydronaphthalene-1-one
7-Methoxy-1-oxotetraline
7-Methoxy-1-tetralinone | [EINECS(EC#)]
229-916-0 | [Molecular Formula]
C11H12O2 | [MDL Number]
MFCD00001696 | [Molecular Weight]
176.21 | [MOL File]
6836-19-7.mol |
| Chemical Properties | Back Directory | [Appearance]
Off-White Powder | [Melting point ]
59-63 °C (lit.) | [Boiling point ]
160-165 C | [density ]
1.124±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | [form ]
Crystalline Powder | [color ]
White to beige | [Water Solubility ]
309mg/L at 25℃ | [BRN ]
2208389 | [InChI]
InChI=1S/C11H12O2/c1-13-9-6-5-8-3-2-4-11(12)10(8)7-9/h5-7H,2-4H2,1H3 | [InChIKey]
GABLTKRIYDNDIN-UHFFFAOYSA-N | [SMILES]
C1(=O)C2=C(C=CC(OC)=C2)CCC1 | [LogP]
2.68 | [CAS DataBase Reference]
6836-19-7(CAS DataBase Reference) | [NIST Chemistry Reference]
7-Methoxy-1-tetralone(6836-19-7) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [HS Code ]
29145000 |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Powder | [Uses]
7-methoxy-1-tetralone was used in the synthesis of 2,7-dimethoxy-1-tetralone, substituted derivatives of 3a,4,5,6-tetrahydrosuccinimido[3,4-b]acenaphthen-10-one and 13H-benzo[6-7]indolo[3,2-c]quinolines. | [Definition]
ChEBI: 7-Methoxy-3,4-dihydro-1(2H)-naphthalenone is a member of tetralins. | [in vivo]
7-Methoxy-1-tetralone (80, 120, or 160 mg/kg/d; ip; 19 doses in total) inhibits tumor growth in subcutaneously implanted tumor model with HepG2 cells[1]. | Animal Model: | BALB/c nude mice (5-week-old) with subcutaneously implanted HepG2 cells[1] | | Dosage: | 80, 120, or 160 mg/kg/d | | Administration: | Intraperitoneal injection; sacrificed after 19 days | | Result: | Resulted the tumor inhibition rates of 40.57% (80 mg/kg), 51.43% (120 mg/kg), 79.43% (160 mg/kg), respectively. |
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