| Identification | Back Directory | [Name]
1,3-Dioxo-2-isoindolineaceticacid | [CAS]
6296-53-3 | [Synonyms]
NSC 16261
NSC 17048
1,3-Dioxo-2
Apremilast inter1
Apremilast Impurity 43
Apremilast Intermediates1
Apremilast Intermediate III
3-AcetaMidophthalic anhydride
3-AcetylaMinophthalic Anhydride
3-Aceta amido pthalic anhydride
3-Acetamidophthalic Anhydride >
3-AcetylaMino-phthalsaeure-anhydrid
N-(1,3-Dioxo-4-isobenzofuranyl)acetaMide
N-(1,3-dioxo-2-benzofuran-4-yl)acetamide
N-(1,3-dioxo-1,3-dihydroisobenzofuran-4-yl)
3-Acetamidophthalic anhydride NSC 16261
1,3-Dioxo-2-isoindolineaceticacid CAS:6296-53-3
N-(1,3-Dihydro-1,3-dioxoisobenzofuran-4-yl)acetamide
N-(1,3-Dioxo-1,3-dihydro-2-benzofuran-4-yl)acetaMide
N-(1,3-dioxo-1,3-dihydroisobenzofuran-4-yl)acetaMide
N-(1,3-Dihydro-1,3-dioxo-4-isobenzofuranyl)acetamide
AcetaMide, N-(1,3-dihydro-1,3-dioxo-4-isobenzofuranyl)-
N-(1,3-Dioxo-1,3-dihydro-2-
benzofuran-4-yl)acetamide Apremilast
RE-EXPORT OF REJECTED IMPORT MATERIAL: N -(1,3-DIHYDROIS OBENZOFURAN-4-YL) ACETAM IDE SYNONYM: 3-ACETAMIDOPHTHALIC ANHYDRI | [EINECS(EC#)]
808-040-8 | [Molecular Formula]
C10H7NO4 | [MDL Number]
MFCD00453138 | [MOL File]
6296-53-3.mol | [Molecular Weight]
205.167 |
| Chemical Properties | Back Directory | [Melting point ]
185-186℃ | [Boiling point ]
489.1±28.0 °C(Predicted) | [density ]
1.512±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
Chloroform (Slightly, Sonicated), Ethyl Acetate (Slightly, Sonicated), Methanol | [form ]
Solid | [pka]
13.81±0.20(Predicted) | [color ]
Off-White to Pale Yellow | [Stability:]
Moisture Sensitive |
| Hazard Information | Back Directory | [Uses]
3-Acetylaminophthalic Anhydride is used in the synthesis of Apremilast, a potent phosphodiesterase 4 and tumor necrosis Factor-α inhibitor used in the treatment of psoriatic arthritis. Also a reagent in the preparation of Tillivalline. Apremilast Impurity 2 |
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