Identification | More | [Name]
DL-Mandelic acid | [CAS]
611-72-3 | [Synonyms]
2-HYDROXY-2-PHENYLACETIC ACID A-HYDROXYBENZENE ACETIC ALPHA-HYDROPHENYLACETIC ACID ALPHA-HYDROXY-ALPHA-TOLUIC ACID (+/-)-ALPHA-HYDROXYPHENYLACETIC ACID ALPHA-HYDROXYPHENYLACETIC ACID DL-2-hydroxy-2-phenylacetic acid DL-A-HYDROXYPHENYLACETIC ACID DL-ALPHA-HYDROXYPHENYLACETIC ACID DL-AMYGDALIC ACID DL-MANDELIC ACID DL-O-HYDROXYPHENYLACETIC ACID DL-PHENYLGLYCOLIC ACID (+/-)-MANDELIC ACID MANDELIC ACID MANDELIC ACID, DL- MANDELIC(D,L-) ACID PHENYLGLYCOLIC ACID PHENYLGLYCOLLIC ACID PHENYLHYDROXYACETIC ACID | [EINECS(EC#)]
202-007-6 | [Molecular Formula]
C8H8O3 | [MDL Number]
MFCD00064250 | [Molecular Weight]
152.15 | [MOL File]
611-72-3.mol |
Safety Data | Back Directory | [Risk Statements ]
R21/22:Harmful in contact with skin and if swallowed . | [Safety Statements ]
S22:Do not breathe dust . S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [RTECS ]
OO6300000
| [HS Code ]
29181980 |
Hazard Information | Back Directory | [Chemical Properties]
Mandelic acid turns brown when exposed to light. It can be esterified easily with alcohols in the presence of hydrogen chloride. | [Physical properties]
(R,S)-Mandelic acid (a-hydroxyphenylacetic acid, phenylglycolic acid), C6H5CH(OH)COOH, C8H8O3, Mr 152.15, mp 118 – 121℃, is a colorless crystalline powder. It is readily soluble in ethanol and diethyl ether, less soluble in chloroform, and insoluble in petroleum ether. Its water solubility is 15 g per 100 mL of water. In alkaline solution, mandelic acid dissolves to form salts. | [Definition]
ChEBI:Mandelic acid is a 2-hydroxy monocarboxylic acid that is acetic acid in which two of the methyl hydrogens are substituted by phenyl and hydroxyl groups. It has a role as an antibacterial agent and a human xenobiotic metabolite. It is a 2-hydroxy monocarboxylic acid and a member of benzenes. It is functionally related to an acetic acid. It is a conjugate acid of a mandelate. | [Production Methods]
(R,S)-mandelic acid is produced
by hydrolysis of mandelic acid nitrile [532-28-5]
(mp 10℃) with hydrochloric acid. Mandelic acid
nitrile is obtained by the conversion of benzaldehyde [100-52-7] and hydrogen cyanide in the
nascent state (NaCN + HCl) under refrigeration.
Another method of producing mandelic acid is the
hydrolysis of a,a-dichloroacetophenone with
alkali. |
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