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ChemicalBook--->CAS DataBase List--->58483-95-7

58483-95-7

58483-95-7 Structure

58483-95-7 Structure
IdentificationBack Directory
[Name]

5-AMINO-2-CHLOROPYRIDINE-4-CARBOXYLIC ACID
[CAS]

58483-95-7
[Synonyms]

5-Amino-2-chloroisonicotinic
3-amino-6-chloroisonicotinicacid
5-amino-2-chloroisonicotinic acid
5-Amino-2-chloropyridine-4-carboxylicaci
5-Amino-2-chloro-4-pyridinecarboxylic acid
5-AMINO-2-CHLOROPYRIDINE-4-CARBOXYLIC ACID
5-Amino-2-Chloroisonicotinic Acid(WXC01548)
4-Pyridinecarboxylic acid, 5-amino-2-chloro-
5-Amino-2-chloropyridine-4-carboxylic acid ,97%
5-AMINO-2-CHLOROPYRIDINE-4-CARBOXYLIC ACID ISO 9001:2015 REACH
5-Amino-2-chloropyridine-4-carboxylic acid, 5-Amino-4-carboxy-2-chloropyridine
[EINECS(EC#)]

687-937-4
[Molecular Formula]

C6H5ClN2O2
[MDL Number]

MFCD06659499
[MOL File]

58483-95-7.mol
[Molecular Weight]

172.57
Chemical PropertiesBack Directory
[Boiling point ]

514.4±50.0 °C(Predicted)
[density ]

1.577±0.06 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Inert atmosphere,2-8°C
[pka]

3.74±0.10(Predicted)
Hazard InformationBack Directory
[Chemical Properties]

Brown powder
[Uses]

3-Amino-6-chloroisonicotinic Acid is a useful synthetic intermediate. It can be used to prepare inhibitors of the EGFr and c-erbB-2. It can also be used to synthesise modulators of GHSr-1a for the treatment of type II diabetes and obesity.
Safety DataBack Directory
[Risk Statements ]

36/37/38
[Safety Statements ]

22-26-36/37/39
[HazardClass ]

IRRITANT
[HS Code ]

29339900
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Hydrochloric acid-->Diethyl ether-->Dichloromethane-->Triethylamine-->Ammonium hydroxide-->n-Butyllithium-->Hexane-->1,4-Dioxane-->Di-tert-butyl dicarbonate-->Carbon dioxide-->Trifluoroacetic acid-->N,N,N',N'-Tetramethylethylenediamine-->5-Amino-2-chloropyridine-->5-[(TERT-BUTOXYCARBONYL)AMINO]-2-CHLOROISONICOTINIC ACID-->5-[N-(TERT-BUTOXYCARBONYL)AMINO]-2-CHLOROPYRIDINE-->2-Amino-5-chloropyridine-->6-Chloronicotinic acid
Spectrum DetailBack Directory
[Spectrum Detail]

5-AMINO-2-CHLOROPYRIDINE-4-CARBOXYLIC ACID(58483-95-7)1HNMR
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