| Identification | More | [Name]
(S)-1-(4-Nitrophenyl)ethylamine hydrochloride | [CAS]
57233-86-0 | [Synonyms]
(R)-(-)-1-(4-NITROPHENYL)-ETHYLAMINE HCL
(R)-1-(4-NITROPHENYL)ETHYLAMINE HYDROCHLORIDE
(R)-4-NITROPHENYL-1-ETHYLAMINE HYDROCHLORIDE
(R)-(-)-ALPHA-METHYL-4-NITROBENZYLAMINE HCL
(R)-ALPHA-METHYL-4-NITROBENZYLAMINE HYDROCHLORIDE
(R)-(+)-ALPHA-METHYL-4-NITROBENZYLAMMONIUM CHLORIDE
(R)-A-METHYL-4-NITROBENZYLAMINE HCL
(R)-(+)-A-METHYL 4-NITROBENZYLAMINE HYDROCHLORIDE
METHYL-4-NITROBENZYLAMINEHYDROCHLORIDE
(R)-4-Nitro-α-methylbenzylamine hydrochloride
Benzenemethanamine, .alpha.-methyl-4-nitro-, monohydrochloride, (.alpha.R)-
(r)-α-methyl-4-nitrobenzylamine hydrochloride
(R)-A-METHYL-4-NITROBENZYLAMINE HYDROCHLORIDE,97%
(S)-1-(4-Nitrophenyl)ethylamine hydrochloride
1-(4-nitrophenyl)ethylamine hydrochloride
(+)-Nitresolve | [Molecular Formula]
C8H11ClN2O2 | [MDL Number]
MFCD00066311 | [Molecular Weight]
202.64 | [MOL File]
57233-86-0.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [F ]
3-10 |
| Hazard Information | Back Directory | [Purification Methods]
To ensure dryness, the hydrochloride (ca 175 g) is extracted with EtOH (3x100mL) and evaporated to dryness (any residual H2O increases the solubility in EtOH and lowers the yield). The hydrochloride residue is triturated with absolute EtOH and dried in vacuo. The product is further purified by refluxing with absolute EtOH (200 mL for 83g) for 1hour, and cool to 10o to give 76.6g of hydrochloride m 243-245o(dec). The free base is prepared by dissolving in N NaOH, extracting with CH2Cl2 (3 x 500mL), drying (Na2CO3), filtering, evaporating and distilling it. It has m 27o, b 119-120o/0.5mm (105-107o/0.5mm, 157-159o/9mm, d 1.1764, n 1.5688, [] ±17.7o (neat) [Perry et al. Synthesis 492 1977,ORD: Nerdel & Liebig Justus Liebigs Ann Chem 621 142 1959]. [Beilstein 12 IV 2451.] |
|
|