| Identification | More | [Name]
Methoxyammonium chloride | [CAS]
593-56-6 | [Synonyms]
HYDROXYLAMINE METHYL ETHER HYDROCHLORIDE
MAH
METHOXYAMINE HCL
METHOXYAMINE HYDROCHLORIDE
methoxyammonium chloride
METHOXYLAMINE HYDROCHLORIDE
METHYLHYDROXYLAMINE HYDROCHLORIDE
METHYOXYAMINE HCL
MOX REAGENT
MOX(TM) REAGENT
O-METHYLHYDROXYAMINE HYDROCHLORIDE
O-METHYLHYDROXYLAMINE HCL
O-METHYLHYDROXYLAMINE HYDROCHLORIDE
O-METHYLHYDROXYLAMMONIUM CHLORIDE
Hydroxylamine,O-methyl-,hydrochloride
methyloxyammoniumchloride
o-methyl-hydroxylaminhydrochloride
Methoxylamine hydrochloride or O-methylhydrolamine
O-METHOXYAMINE HCL
METHOXYLAMINE HYDROCHLORIDE, 25-30 WT. % SOLUTION IN WATER | [EINECS(EC#)]
209-798-7 | [Molecular Formula]
CH6ClNO | [MDL Number]
MFCD00012951 | [Molecular Weight]
83.52 | [MOL File]
593-56-6.mol |
| Chemical Properties | Back Directory | [Appearance]
White to very faintly yellow crystalline powder | [Melting point ]
151-154 °C(lit.)
| [Boiling point ]
105-110°C | [density ]
1.1 g/mL at 25 °C
| [refractive index ]
n20/D 1.4021
| [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
alcohol: soluble(lit.) | [form ]
Crystalline Powder | [color ]
White to very faint yellow | [Water Solubility ]
SOLUBLE | [Sensitive ]
Hygroscopic | [Detection Methods]
T,NMR,HPLC(Differential) | [Merck ]
14,5989 | [BRN ]
3589723 | [InChIKey]
XNXVOSBNFZWHBV-UHFFFAOYSA-N | [CAS DataBase Reference]
593-56-6(CAS DataBase Reference) | [EPA Substance Registry System]
593-56-6(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
C,Xi,N | [Risk Statements ]
R34:Causes burns.
R36/37/38:Irritating to eyes, respiratory system and skin .
R50:Very Toxic to aquatic organisms.
R43:May cause sensitization by skin contact.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S3:Keep in a cool place .
S24:Avoid contact with skin .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S24/25:Avoid contact with skin and eyes .
S27:Take off immediately all contaminated clothing . | [RIDADR ]
UN 3265 8/PG 2
| [WGK Germany ]
3
| [RTECS ]
NC3980000
| [F ]
3-10 | [Hazard Note ]
Corrosive/Hygroscopic | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29280000 |
| Hazard Information | Back Directory | [General Description]
Off-white crystals. | [Reactivity Profile]
In aqueous solution, O-METHYLHYDROXYLAMINE HYDROCHLORIDE(593-56-6) behaves as an acid. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions. | [Air & Water Reactions]
Water soluble. | [Fire Hazard]
Flash point data for this chemical are not available. O-METHYLHYDROXYLAMINE HYDROCHLORIDE is probably combustible. | [Description]
Methoxamine hydrochloride, also known as methoxamine hydrochloride, O-methyl hydroxylamine hydrochloride. It is a white crystalline powder, and its fusing point is 149 ~ 152 DEG C, soluble in water, dissolved in alcohol, insoluble in ether and toluene, etc., and the solution is in acid. Methoxamine hydrochloride is an important chemical and medicine intermediate, can be used for the development and printing of color photography and film, and is widely used in the synthesis of medicine, functional dye, low-toxin farm chemicals, and new herbicides. Methoxamine hydrochloride is mainly used in the synthesis of s-generation cephalosporin product cephalofruxin in medical, and sulfamethoxazole; alkynes promise are bright, the synthesis of hydroxyurea, etc.; Agricultural chemicals aspect is then mainly used in the kresoxim-methyl of synthesizing efficient low toxicity. | [Chemical Properties]
White to very faintly yellow crystalline powder | [Uses]
antineoplastic, hydroxymethyltransferase inhibitor | [Uses]
Methoxylamine is a methoxime derivative used as internal standard for Prostaglandin assays by gas chromatography-mass spectrometry | [Purification Methods]
Crystallise the hydrochloride from absolute EtOH or EtOH by addition of diethyl ether. [Kovach et al. J Am Chem Soc 107 7360 1985, Beilstein 1 IV 1252.] |
| Questions And Answer | Back Directory | [Methoxyamine hydrochloride]
Methoxyamine hydrochloride (also known as O-methylhydroxylamine hydrochloride; Methoxyamine; Methoxyamine hydrochloride (OMHA), is an important medicine, pesticide intermediates. Its major applications are as follows:
- it can be used for color photography and film printing.
- it is used as a reducing agent in organic synthesis industry for preparation of oximes.
- the field of medicine: it can be used for the synthesis of second-generation cephalosporins antibiotics cefuroxime (ester), neopropene, norethindine and hydroxyurea.
- the field of pesticides: the synthesis of new efficient, low-toxicity bactericidal metominostrobin.
- It is mainly produced by sodium nitrite method in our country.
The similar compound of methoxyamine hydrochloride, the ethoxylamine hydrochloride is mainly used for the production of herbicides, oxycarbazone, diltiazem and other herbicides. | [Application]
- Used as a methoxyamine reagent, also used in the production of the side chain of Cefuroxime and other new drugs
- Used for pesticide synthesis.
- Use for pharmaceuticals production
- Used for the preparation of O-methyloxime together with aldehydes or ketones.
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