| Identification | Back Directory | [Name]
OTAVA-BB 1207229 | [CAS]
571188-59-5 | [Synonyms]
POB02
OTAVA-BB
Ribociclib-2
PALBOCICLIB4
Palbociclib-11
Palbociclib-018
OTAVA-BB 1207229
)piperazine-1-carboxyL
Palbociclib side chain
Palbociclib Impurity 68
4-(6-aMinopyridin-3-yl)p
Palbociclib Intermediate
tert-butyl 4-(6-aMinopyri
Palbociclib's intermediate
Ribociclib Related Compound 1
1-Boc-4-(6-amino-3-pyridyl)piperazine
4-(6-Amino-3-pyridyl)-1-Boc-piperazine
1-BOC-4-(6-AMINOPYRIDIN-3-YL)PIPERAZIN
1-BOC-4-(6-AMINOPYRIDIN-3-YL)PIPERAZINE
4-(6-AMinopyridin-3-yl)-1-Boc-piperazine
4-(6-aMinopyridin-3-yl)piperazine-1-carboxylic
4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)- (acetate)
1-Butyloxycarbonyl-4-(6-aminopyridin-3-yl)-piperazine
1-tert-Butoxycarbonyl-4-(6-amino-3-pyridyl)piperazine
Tert-Butyl 4-(6-aminopyridin-3-piperazine-1-carboxylate
Tert-buty 4-(6-amino-3-pyridyl)piperazine-1-carboxylate
6-(6-Aminopyridin-3-yl)piperazine, N1-BOC protected 98%
t-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
tert-butyl 4-(6-amino-3-pyridyl)piperazine-1-carboxylate
OTAVA-BB 1207229/1-Boc-4-(6-aminopyridin-3-yl)piperazine
ert-Butyl4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
1-(tert-Butoxycarbonyl)-4-(6-aminopyridin-3-yl)piperazine
tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
tert-butyl 4-(6-aminoyridin-3-yl)pipera-zine-1-carboxylate
Tert-Butyl 4-(6-Amino-3-Pyrimidin)Piperazine-1-Carboxylate
tert-Butyl 4-(6-Amino-3-pyridyl)piperazine-1-carboxylate >
tert-Butyl 4-(6-Amino-3-pyridyl)piperazine-1-carboxylate
4-(6-aminopyridine-3-yl) piperazine-1-carboxylic tert-butyl ester
4-(6- aminopyridine -3- yl) piperazine -1- tert-butyl carboxylate
4-(6-Amino-3-pyridyl)piperazine-1-carboxylic Acid tert-Butyl Ester
2-Methyl-2-propanyl 4-(6-amino-3-pyridinyl)-1-piperazinecarboxylate
4-(6-Aminopyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester
OTAVA-BB 1207229/1-Boc-4-(6-aminopyridin-3-yl)piperazine(571188-59-5)
4- (6-aminopyridine-3-yl) piperazin-1-carboxylic acid tert-butyl ester
tert-butyl 4-(6-amino-3-pyridyl)piperazine-1-carboxylate(For Palbociclib)
OTAVA-BB 1207229
tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
1-Piperazinecarboxylic acid, 4-(6-aMino-3-pyridinyl)-, 1,1-diMethylethyl ester
Palbociclib Intermediate 1, tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate | [EINECS(EC#)]
695-268-4 | [Molecular Formula]
C14H22N4O2 | [MDL Number]
MFCD11594962 | [MOL File]
571188-59-5.mol | [Molecular Weight]
278.354 |
| Chemical Properties | Back Directory | [Melting point ]
130-132℃ | [Boiling point ]
454.1±45.0 °C(Predicted) | [density ]
1.182 | [vapor pressure ]
0-0Pa at 20-25℃ | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
DMSO (Slightly), Methanol (Very Slightly) | [form ]
Solid | [pka]
7.36±0.26(Predicted) | [color ]
Dark Yellow | [Sensitive ]
Air Sensitive | [InChI]
InChI=1S/C14H22N4O2/c1-14(2,3)20-13(19)18-8-6-17(7-9-18)11-4-5-12(15)16-10-11/h4-5,10H,6-9H2,1-3H3,(H2,15,16) | [InChIKey]
RMULRXHUNOVPEI-UHFFFAOYSA-N | [SMILES]
N1(C(OC(C)(C)C)=O)CCN(C2=CC=C(N)N=C2)CC1 | [LogP]
1.6-1.8 at 35℃ and pH7-9 |
| Hazard Information | Back Directory | [Uses]
4-(6-Amino-3-pyridyl)-1-Boc-piperazine is used as an organic chemical synthesis intermediate. | [Preparation]
4- (6-Nitro-pyridin-3-yl)-piperazine-1 -carboxylic acid ie f-butyl ester and Pd/C in ethanol is stirred with an H2 balloon for 3 h. The product tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate is obtained through purification.
 | [Hazard]
Causes skin irritation
Causes serious eye irritation
May cause respiratory irritation |
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