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ChemicalBook--->CAS DataBase List--->56796-39-5

56796-39-5

56796-39-5 Structure

56796-39-5 Structure
IdentificationMore
[Name]

Cefmetazole sodium
[CAS]

56796-39-5
[Synonyms]

CEFMETAZOLE
Cefmetazone
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R,7S)-
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R-cis)-
Cefmetazole-Na
CS-1170 sodium salt
Metafar
Sodium cefmetazole
Cefmetazole sodium
Sodium (6R,7S)-7-[[2-(cyanomethylsulfanyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
(6R,7S)-7-[[2-[(Cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Sodium Salt
(6R)-7-[[[(Cyanomethyl)thio]acetyl]amino]-7β-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt
[EINECS(EC#)]

627-393-7
[Molecular Formula]

C15H17N7O5S3
[MDL Number]

MFCD00865068
[Molecular Weight]

471.53
[MOL File]

56796-39-5.mol
Chemical PropertiesBack Directory
[Appearance]

White Solid
[Melting point ]

>130°C (dec.)
[storage temp. ]

2-8°C
[solubility ]

H2O: soluble50mg/mL
[form ]

powder
[color ]

White to Off-White
[Water Solubility ]

Soluble in water
[Sensitive ]

Hygroscopic
[Usage]

Semi-synthetic antibiotic derived from Cephamycin. Antibacterial
[Merck ]

14,1926
[Stability:]

Hygroscopic
[InChIKey]

BITQGIOJQWZUPL-PBCQUBLHSA-M
[CAS DataBase Reference]

56796-39-5(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xn,Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
R42/43:May cause sensitization by inhalation and skin contact .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
[WGK Germany ]

2
[RTECS ]

XI0372200
[HS Code ]

2941.90.3000
[Toxicity]

LD50 i.v. in rats: >5000 mg/kg (Masuda)
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Uses]

Semi-synthetic antibiotic derived from Cephamycin. Antibacterial
[Definition]

ChEBI: An organic sodium salt that is the sodium salt of cefmetazole.
[Brand name]

Zefazone (Pharmacia & Upjohn).
[Clinical Use]

Cefmetazole (Zefazone) is a semisynthetic, third-generation,parenteral cephalosporin of the cephamycin group. Likeother cephamycins, the presence of the 7α-methoxyl groupconfers resistance to many β-lactamases. Cefmetazoleexhibits significantly higher potency against members ofthe Enterobacteriaceae family but lower activity againstBacteroides spp. than cefoxitin. It is highly active againstN. gonorrhoeae, including -lactamase–producing strains. Incommon with other cephamycins, cefmetazole is ineffectiveagainst indole-positive Proteus, Enterobacter, Providencia,Serratia, and Pseudomonas spp. Cefmetazole has the MTTmoiety associated with increased bleeding in certain highriskpatients. It has a plasma half-life of 1.1 hours.
[storage]

4°C, away from moisture and light
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

56796-39-5(sigmaaldrich)
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