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ChemicalBook--->CAS DataBase List--->56512-49-3

56512-49-3

56512-49-3 Structure

56512-49-3 Structure
IdentificationMore
[Name]

DABSYL CHLORIDE
[CAS]

56512-49-3
[Synonyms]

4-DIMETHYLAMINOAZOBENZENE-4'-SULFONYL CHLORIDE
4-DIMETHYLAMINOAZOBENZENE-4-SULFONYL-CHLORIDE
4-DIMETHYLAMINOAZOBENZENE-4'-SULPHONYL CHLORIDE
4-DIMETHYLAMINOAZOBENZENE-4-SULPHONYL CHLORIDE
DABS-CL
DABSYL CHLORIDE
4-((4-(dimethylamino)phenyl)azo)-benzenesulfonylchlorid
4-[[4-(dimethylamino)phenyl]azo]-benzenesulfonylchlorid
4-n,n-dimethylaminoazobenzene-4’-sulfonylchloride
p-((p-(dimethylamino)phenyl)azo)-benzenesulfonylchlorid
p-[[4-(dimethylamino)phenyl]azo]benzenesulphonyl chloride
DABSYL CHLORIDE, 500MG, NEAT
4-(4-Dimethylaminophenylazo)benzenesulfonyl chloride
4-(DIMETHYLAMINO)AZOBENZENE-4-SULFONYL
Dabsyl
Benzenesulfonyl chloride, 4-4-(dimethylamino)phenylazo-
PARA-DIMETHYLAMINOAZOBENZENE-4-SULPHONYLCHLORIDE-4
4-DIMETHYLAMINOAZOBENZENE-4''-SULFONYL CHLORIDE [N-PROTECTING AGENT FOR PEPTIDES RESEARCH] 98+%
4-Dimethylaminoazobenzene-4'-sulfonyl chloride, 98+%
Dabsyl Chloride [N-Protecting Agent for Peptides Research]
[EINECS(EC#)]

260-235-1
[Molecular Formula]

C14H14ClN3O2S
[MDL Number]

MFCD00007444
[Molecular Weight]

323.8
[MOL File]

56512-49-3.mol
Chemical PropertiesBack Directory
[Melting point ]

185 °C (dec.) (lit.)
[Boiling point ]

483.6±30.0 °C(Predicted)
[density ]

1.29±0.1 g/cm3(Predicted)
[storage temp. ]

−20°C
[solubility ]

DMF: soluble
[pka]

3.27±0.10(Predicted)
[Sensitive ]

Moisture Sensitive
[BRN ]

3064095
[CAS DataBase Reference]

56512-49-3(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

C
[Risk Statements ]

R34:Causes burns.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S27:Take off immediately all contaminated clothing .
[RIDADR ]

UN 3261 8/PG 2
[WGK Germany ]

3
[RTECS ]

DB8927800
[F ]

10-21
[HazardClass ]

8
[PackingGroup ]

II
[HS Code ]

29270000
Hazard InformationBack Directory
[Chemical Properties]

Dark red crystalline
[Uses]

For the qualitative and quantitative identification of amino acids and for the determination of N-terminal amino acids. Used in the determination of primary and secondary amines by HPLC.
[General Description]

Amino groups are common to many biological compounds and many amines used in pharmaceuticals. Most of these compounds show weak absorption in direct HPLC analysis with UV-VIS detection. However, strongly absorbing derivatives of amines can be easily detected by HPLC with high sensitivity even when present at low concentrations. Primary and secondary amino groups are usually derivatized as aromatic derivatives by nucleophilic substitution reactions using reagents such as arylsulfonyl chlorides.
4-(Dimethylamino)azobenzene-4′-sulfonyl chloride, a well-known UV-labeling agent, is generally used for the derivatization of N-terminal amino acids, imidazole derivatives, polyamines, etc. prior to their chromatographic determination due to the former′s capacity to covalently bind to the substrates. Its derivatives typically absorb UV radiation between the range of 436-460 nm. This method of derivatization is regarded as superior compared to other methods owing to the simplicity of the procedure, high stability and reproducibility, best resolution of the analytes, etc.
Spectrum DetailBack Directory
[Spectrum Detail]

DABSYL CHLORIDE(56512-49-3)MS
DABSYL CHLORIDE(56512-49-3)1HNMR
DABSYL CHLORIDE(56512-49-3)IR1
DABSYL CHLORIDE(56512-49-3)IR2
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

[Sigma Aldrich]

56512-49-3(sigmaaldrich)
[TCI AMERICA]

Dabsyl Chloride  [N-Protecting Agent for Peptides Research],>98.0%(T)(56512-49-3)
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