| Identification | More | [Name]
Solvent Yellow 2 | [CAS]
60-11-7 | [Synonyms]
4-DIMETHYLAMINOAZOBENZENE
4-(N,N-DIMETHYLAMINO)-AZOBENZENE
Benzeneazodimethylaniline
BROMOCRESOL GREEN-METHYL YELLOW
BUTTER YELLOW
CI 11020
CI NO 11020
DIMETHYL YELLOW
FAST YELLOW
LABOTEST-BB LT00847286
METHYL YELLOW
METHYL YELLOW-BROMOCRESOL GREEN
METHYL YELLOW ETHANOL(90)
N,N-DIMETHYL-4-(PHENYLAZO)ANILINE
N,N-DIMETHYL-P-PHENYLAZOANILINE
OIL YELLOW
OIL YELLOW D
OIL YELLOW GR
OIL YELLOW II
P-DIMETHYLAMINOAZOBENZENE | [EINECS(EC#)]
200-455-7 | [Molecular Formula]
C14H15N3 | [MDL Number]
MFCD00008308 | [Molecular Weight]
225.29 | [MOL File]
60-11-7.mol |
| Chemical Properties | Back Directory | [Definition]
A banned food coloring. | [Appearance]
yellow to orange crystalline powder | [Melting point ]
111 °C (dec.)(lit.) | [Boiling point ]
356.8°C (rough estimate) | [density ]
1.1303 (rough estimate) | [vapor pressure ]
3 x 10-7 mmHg (estimated, NIOSH, 1997) | [refractive index ]
1.5770 (estimate) | [storage temp. ]
Store at RT. | [solubility ]
Insoluble in water; soluble in ethanol, benzene, ether, chloroform,petroleum ether, mineralacids, oils | [Colour Index ]
11020 | [form ]
Powder | [pka]
3.226(at 25℃) | [color ]
Yellow | [PH]
2.9-4.0 | [PH Range]
2.9(red)-4(yellow/orange) | [Stability:]
Stable, but heat and light sensitive. Incompatible with strong oxidizing agents, strong acids. | [Water Solubility ]
13.6 mg/L | [λmax]
408nm, 256nm, 508nm | [Merck ]
14,3229 | [BRN ]
746016 | [Major Application]
Electrochromic materials, sol-gel coatings, display device, inks, gasdetection apparatus, status assessment indetection apparatus, nematocides, hair dyes, diapers, food storage, status assessment inbreast cancer, detecting carbohydrates, bacteria, diagnosing cervical disease, wound dressing materials | [CAS DataBase Reference]
60-11-7(CAS DataBase Reference) | [IARC]
2B (Vol. 8, Sup 7) 1987 | [NIST Chemistry Reference]
Benzenamine, N,N-dimethyl-4-(phenylazo)-(60-11-7) | [EPA Substance Registry System]
60-11-7(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
R25:Toxic if swallowed.
R40:Limited evidence of a carcinogenic effect.
R68:Possible risk of irreversible effects.
R45:May cause cancer.
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S53:Avoid exposure-obtain special instruction before use .
S22:Do not breathe dust . | [RIDADR ]
UN 2811 6.1/PG 3
| [WGK Germany ]
3
| [RTECS ]
BX7350000
| [TSCA ]
Yes | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29270000 | [Safety Profile]
Confirmed carcinogen
with experimental carcinogenic,
neoplastigenic, and tumorigenic data. Poison
by ingestion and intraperitoneal routes.
Experimental teratogenic and reproductive
effects. Human mutation data reported.
When heated to decomposition it emits
toxic fumes of NOx | [Hazardous Substances Data]
60-11-7(Hazardous Substances Data) | [Toxicity]
Acute oral LD50 for mice 300 mg/kg, rats 200 mg/kg (quoted, RTECS, 1985). |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
Sodium acetate-->benzenediazonium-->N,N,N',N'-tetramethyl-4,4'-azodianiline-->N,N-DIMETHYL-4-NITROANILINE-->1-[4-(dimethylamino)phenyl]propan-1-ol-->PHENYL AZIDE-->4,4'-Methylenebis(N,N-dimethylaniline)-->N,N-DIMETHYL-4-NITROSOANILINE-->N,N-Dimethyl-1,4-phenylenediamine-->N,N-Dimethylaniline-->Aniline | [Preparation Products]
Diazene, 1,2-diphenyl-, stereoisomer |
| Hazard Information | Back Directory | [General Description]
Yellow crystalline leaflets or an orange powder. | [Reactivity Profile]
4-DIMETHYLAMINOAZOBENZENE(60-11-7) can detonate, particularly if sensitized by the presence of metal salts or strong acids. May form toxic gases with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. May form flammable gases with alkali metals. May react explosively with strong oxidizing agents, metal salts, peroxides, and sulfides. May react explosively with strong oxidizing agents, metal salts, peroxides, and sulfides. | [Air & Water Reactions]
Dust may form an explosive mixture in air. Insoluble in water. | [Hazard]
Carcinogen. | [Fire Hazard]
Flash point data for this chemical are not available. 4-DIMETHYLAMINOAZOBENZENE is probably combustible. | [Description]
4-N,N-Dimethylaminobenzene diazonium chloride is a
diazo compound found in diazo copy paper. It is
allergenic only when unexposed.
| [Chemical Properties]
yellow to orange crystalline powder | [Uses]
Butter yellow was largely used as a food coloring agent. It was
also used for the determination of free hydrochloric acid in
gastric juice, for the spot test identification of peroxidized fats,
as a pH indicator, and as a laboratory reagent. | [Uses]
For determination of free HCl in gastric juice; spot test identification of peroxidized fats; pH indicator (red 2.9, yellow 4.0). | [Uses]
Formerly used as a coloring agent in
foods, drugs, and cosmetics | [Preparation]
aniline diazotization, and N,N-dimethylaniline coupling. | [Production Methods]
4-Dimethylaminoazobenzene was produced in large quantities
in the early 1900s but is currently not produced in
any significant commercial quantity in the United States. | [Health Hazard]
4-Dimethylamino-azobenzene (XIII) is the parent compound of the amino-azo dye carcinogens; it is also known in the earlier literature as Butter Yellow, because it was used to color butter and vegetable oils before its carcinogenic activity was discovered. Many derivatives of XIII have been prepared and tested for carcinogenic activity. In the rat, the amino-azo dye carcinogens, administered in the diet, specifically induce hepatomas. Tumor induction by most of the amino-azo dyes is delayed or inhibited by high dietary levels of riboflavin (vitamin B2) or protein. Replacement of the –N=N– azo linkage by –CH=CH–, as in 4-dimethylaminostilbene (XIV), results in widening the target tissue spectrum; XIV induces tumors in the liver, mammary gland, and ear duct. Mice are much more resistant than rats to the carcinogenic activity of both amino-azo dyes and aminostilbenes. | [Potential Exposure]
Tumorigen,Drug, Mutagen; Reproductive Effector DAB is used for coloring polishes and other wax products, polystyrene, petrol,soap, and as a chemical indicator. Human exposure to DABcan occur through either inhalation or skin absorption. | [First aid]
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. Contact a physician, hospital, or poison center atonce. If the victim is unconscious or convulsing, do notinduce vomiting or give anything by mouth. Assure that thepatient’s airway is open and if conscious and not convulsing, give a glass of water to dilute the substance. Vomitingshould not be induced without a physician’s advice. | [Carcinogenicity]
4-Dimethylaminoazobenzene is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity fromstudies in experimental animals. | [Environmental Fate]
Chemical/Physical. Releases toxic nitrogen oxides when heated to decomposition (Sax and
Lewis, 1987).
At influent concentrations of 1.0, 0.1, 0.01, and 0.001 mg/L, the GAC adsorption capacities
were 249, 140, 83, and 48 mg/g, respectively (Dobbs and Cohen, 1980). | [storage]
Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with DAB youshould be trained on its proper handling and storage. Storein a cool, dry place and protect from exposure to light andair. A regulated, marked area should be established wherethis chemical is handled, used, or stored in compliance withOSHA Standard 1910.1045. | [Shipping]
Dyes, solid, toxic, n.o.s. require a label of“POISONOUS/TOXIC MATERIALS.” 4-Dimethylaminoazo-benzene falls in Hazard Class 6.1; Packing Group III. | [Properties and Applications]
yellow to red light yellow. Light yellow powder, melting point 115 ℃ (yellow flaky crystal). Insoluble in water, soluble in ethanol for yellow solution, in oil soluble. In concentrated sulfuric acid to yellow, red after diluted solution; . Mainly used for Aviation fuel TETRAETHYLLEAD stability agent and pH indicator, also used in paraffin, polystyrene, oil and soap stain
|
Standard
|
Light Fastness
|
Heat-resistant(℃)
|
Water
|
Sodium Carbonate(5%)
|
Hydrochloric acid(5%)
|
|
Melting point
|
Stable
|
|
ISO
|
General
|
113.5-115
|
120
|
Poor
|
Well
|
Poor
|
| [Purification Methods]
Crystallise the dye from acetic acid or isooctane, or from 95% EtOH by adding hot water and cooling. Dry it over KOH under vacuum at 50o. [Beilstein 6 IV 448.] CARCINOGEN. | [Toxicity evaluation]
Butter yellow exists as a stable crystalline material at normal
temperature and pressure. It is insoluble in water, but soluble in
organic solvents such as alcohol, chloroform, ether, petroleum
ether, mineral acids, oils, and pyridine. Its octanol/water partition
coefficient is 4.58, vapor pressure is 3.3×10-7 mm Hg;
and Henry’s law constant is 7.1×10-9 atm-m3 mol-1.
Butter yellow may be released into the environment as
a result of its manufacture and use in the consumer products.
It may bind to the soil and when released into water, may
bioconcentrate in aquatic organisms, or may be adsorbed into
the sediment. If released in the atmosphere, it may undergo
direct photolysis. | [Incompatibilities]
None reported. |
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