| Identification | More | [Name]
DL-Pipecolinic acid | [CAS]
535-75-1 | [Synonyms]
(+/-)-2-PIPERIDINECARBOXYLIC ACID
2-PIPERIDINECARBOXYLIC ACID
DL-2-PIPERIDINECARBOXYLIC ACID
DL-HOMOPROLINE
DL-PIPECOLIC ACID
DL-PIPECOLINIC ACID
DL-PIPECOLONIC ACID
DL-PIPERCOLINIC ACID
H-DL-HOMOPRO-OH
H-DL-HOPRO-OH
H-DL-PIC(2)-OH
LABOTEST-BB LT00847911
PIPECOLIC ACID
PIPECOLINIC ACID
(+/-)-PIPERIDINE-2-CARBOXYLIC ACID
PIPERIDINE-2-CARBOXYLIC ACID
RAC PIPERIDINE-2-CARBOXYLIC ACID
RARECHEM AH CK 0177
acidepipecolique
acidepiperidine-carboxylique-2 | [EINECS(EC#)]
208-616-3 | [Molecular Formula]
C6H11NO2 | [MDL Number]
MFCD00064347 | [Molecular Weight]
129.16 | [MOL File]
535-75-1.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light beige fine crystalline powder | [Melting point ]
282 °C (dec.)(lit.)
| [alpha ]
[α]D20 -1～+1° (c=2.5, H2O) | [Boiling point ]
239.22°C (rough estimate) | [density ]
1.1426 (rough estimate) | [refractive index ]
1.4587 (estimate) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Methanol (Slightly), Water (Slightly) | [form ]
Fine Crystalline Powder | [pka]
2.28, 10.72(at 25℃) | [color ]
White to light beige | [Water Solubility ]
soluble | [Detection Methods]
T,NMR | [Merck ]
14,7458 | [BRN ]
81095 | [InChIKey]
HXEACLLIILLPRG-UHFFFAOYSA-N | [CAS DataBase Reference]
535-75-1(CAS DataBase Reference) | [EPA Substance Registry System]
535-75-1(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [RTECS ]
TK6021000 | [TSCA ]
T | [HazardClass ]
IRRITANT | [HS Code ]
29339900 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light beige fine crystalline powder | [Uses]
Pipecolic acid is involved in synaptic transmission in the central nervous system. | [Definition]
ChEBI: A piperidinemonocarboxylic acid in which the carboxy group is located at position C-2. | [reaction suitability]
reaction type: solution phase peptide synthesis | [in vivo]
Pipecolic acid (intragastric administration; 250 mg/kg; 1 week) can improve diabetic retinopathy in mouse model[2]. | Animal Model: | Male wild-type C57BL/6 mice aged 8 weeks old with Diabetic retinopathy (DR)[3] | | Dosage: | 250 mg/kg | | Administration: | Intragastric administration; 1 week | | Result: | Had positive effects on weight gain and blood sugar level in mice.
Significantly reduced the ratio of retinal positive areas to whole positive areas.
Regulated oxidative stress and iron metabolism.
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