| Identification | More | [Name]
DL-Histidine | [CAS]
4998-57-6 | [Synonyms]
(+/-)-2-AMINO-3-(4-IMIDAZOLYL)PROPIONIC ACID
AKOS BBS-00004484
DL-2-AMINO-3-(4-IMIDAZOLYL)PROPIONIC ACID
DL-ALPHA-AMINO-BETA-IMIDAZOLEPROPIONIC ACID
DL-HISTIDINE
H-DL-HIS-OH
HISTIDINE
HISTIDINE, DL-
DL-Histidine, Free Base
α-Amino-4/5-imidazolepropionic acid
DL-Histidin
DL-2-Amino-3-(1H-imidazol-4-yl)propanoic acid
1H-Imidazole-4-alanine
D-Histidine/L-histidine,(1:1)
rac-(R*)-2-Amino-3-(4-imidazolyl)propionic acid | [EINECS(EC#)]
225-660-9 | [Molecular Formula]
C6H9N3O2 | [MDL Number]
MFCD00005208 | [Molecular Weight]
155.15 | [MOL File]
4998-57-6.mol |
| Chemical Properties | Back Directory | [Appearance]
white to slightly yellow crystalline powder | [Melting point ]
273 °C (dec.)(lit.) | [Boiling point ]
278.95°C (rough estimate) | [density ]
1.3092 (rough estimate) | [refractive index ]
1.6500 (estimate) | [storage temp. ]
Store at RT. | [solubility ]
0.5 M HCl: soluble | [pka]
1.8(at 25℃) | [Merck ]
4720 | [BRN ]
7800 | [Uses]
histidine is a skin-conditioning amino acid. | [CAS DataBase Reference]
4998-57-6(CAS DataBase Reference) | [EPA Substance Registry System]
4998-57-6(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S36/37:Wear suitable protective clothing and gloves .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [HS Code ]
29339900 |
| Hazard Information | Back Directory | [Chemical Properties]
white to slightly yellow crystalline powder | [Definition]
ChEBI: An alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 67, p. 502, 1945 DOI: 10.1021/ja01219a513
Chemical and Pharmaceutical Bulletin, 35, p. 3447, 1987 | [Biochem/physiol Actions]
L-Histidine is involved in the one-carbon unit metabolism. It is associated with protein methylation. L-Histidine is a part of hemoglobin structure and function. L-Histidine is a component of dipeptides with antioxidative property. Histidine serves as a precursor for the formation of histamine, which is associated with allergic responses. Urocanic acid, an immune response modulator in skin is also biosynthesised from histidine. |
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