| Identification | Back Directory | [Name]
Ethyl 4-hydroxypyrimidine-5-carboxylate | [CAS]
4786-52-1 | [Synonyms]
7-chloroisoquinolin-1(2H)-one
ethyl 6-oxo-1H-pyrimidine-5-carboxylate
ETHYL 4-HYDROXYPYRIMIDINE-5-CARBOXYLATE
4-hydroxy-5-pyrimidinecarboxylicaciethylester
Ethyl 1,4-dihydro-4-oxo-5-pyrimidinecarboxylate
6-Hydroxypyrimidine-5-carboxylic acid ethyl ester
6-keto-1H-pyrimidine-5-carboxylic acid ethyl ester
4-HYDROXY-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER
Ethyl 6-oxo-1,6-dihydropyrimidine-5-carboxylate LR
6-OXO-1,6-DIHYDRO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER
Ethyl 4-hydroxypyrimidine-5-carboxylate ISO 9001：2015 REACH
5-Pyrimidinecarboxylic acid, 1,6-dihydro-6-oxo-, ethyl ester
5-Pyrimidinecarboxylic acid, 1,4-dihydro-4-oxo-, ethyl ester
4-Hydroxy-pyrimidine-5-carboxylic acid ethyl ester (HCl salt) | [Molecular Formula]
C7H8N2O3 | [MDL Number]
MFCD00235034 | [MOL File]
4786-52-1.mol | [Molecular Weight]
168.15 |
| Chemical Properties | Back Directory | [Melting point ]
185-186 °C | [density ]
1.33±0.1 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,Room Temperature | [pka]
7.70±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
7-Chloroisoquinolin-1(2H)-one acts as a reagent for the preparation, SAR of methoxyisoquinoline derivative and discovery of asunaprevir (BMS-650032), an orally efficacious NS3 protease inhibitor for the treatment of hepatitis C virus infection. Synthesis and pharmacological evaluation of a series of 1,2-dihydro-1-[(5-methyl-1-imidazol-4-yl)methyl]-2-oxopyridine 5-HT3 antagonists. |
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