| Identification | More | [Name]
Asiatic acid | [CAS]
464-92-6 | [Synonyms]
(1s,2r,4as,6ar,6as,6br,8ar,9s,10s,11r,12as,14br)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1h-picene-4a-carboxylic acid
2,3,23-TRIHYDROXY-12-URSEN-28-OIC ACID
ASIATIC ACID
URS-12-EN-28-OIC ACID, 2,3,23-TRIHYDROXY-, (2A,3B,4A)-
ASIATICACID:URS-12-EN-28-OICACID, 2,3,23-TRIHYDROXY-, (2A,3B,4A)-,
Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2.alpha.,3.beta.,4.alpha.)-
ASIATIC ACID(P)
Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2α,3β,4α)-
(1S,2R,4aS,6aR,6aS,6bR,8aR,9S,10S,11R,12aS,14bR)-10,11-Dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
2α,3β,23-Trihydroxyurs-12-en-28-oicacid
(4R)-2α,3β,23-Trihydroxyurs-12-en-28-oic acid
2α,3β,23-Trihydroxyurs-12-ene-28-oic acid
Asiantic acid | [EINECS(EC#)]
482-720-9 | [Molecular Formula]
C30H48O5 | [MDL Number]
MFCD00238541 | [Molecular Weight]
488.7 | [MOL File]
464-92-6.mol |
| Chemical Properties | Back Directory | [Melting point ]
325-330 °C(lit.)
| [Boiling point ]
609.4±55.0 °C(Predicted) | [density ]
1.18±0.1 g/cm3(Predicted) | [RTECS ]
YU9580000 | [storage temp. ]
2-8°C | [solubility ]
methanol: soluble1mg/mL, clear, colorless | [form ]
powder | [pka]
4.66±0.70(Predicted) | [color ]
white | [biological source]
Centella asiatica | [Water Solubility ]
Soluble in dimethyl sulfoxide, ethanol and dimethylformamide. Sparingly soluble in water | [InChIKey]
JXSVIVRDWWRQRT-UYDOISQJSA-N | [LogP]
5.748 (est) | [CAS DataBase Reference]
464-92-6(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Uses]
Asiatic Acid is a terpenoid with an ursane skeleton isolated from Centella asiatica. Asiatic Acid is a neuroprotectant and induces of apoptosis in HepG2 human hepatoma cells. | [Uses]
wound healing, experimental carcinogen | [Definition]
ChEBI: A pentacyclic triterpenoid that is ursane substituted by a carboxy group at position 28 and hydroxy groups at positions 2, 3 and 23 (the 2alpha,3beta stereoisomer). It is isolated from Symplocos lancifolia and
Vateria indica and exhibits anti-angiogenic activity. | [General Description]
Asiatic acid is a naturally occurring pentacyclic triterpenoid, obtained from Centella asiatica. | [Biochem/physiol Actions]
Asiatic acid is commonly used in wound healing. Asiatic acid has antioxidant, anti-inflammatory and neuroprotective properties. | [target]
TNF-α | IFN-γ | IL Receptor | Caspase | p21 | NOS | NADPH-oxidase | NO | HMG-CoA reductase | COX |
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