| Identification | More | [Name]
N,N-Dimethylformamide dimethyl acetal | [CAS]
4637-24-5 | [Synonyms]
1,1-DIMETHOXY-N,N-DIMETHYL METHANAMINE
1,1-DIMETHOXY-N,N-DIMETHYLMETHYLAMINE
1,1-DIMETHOXYTRIMETHYLAMINE
AURORA KA-683
DIMETHYLFORMAMIDEDIMETHYLACETAL
DMF-DIMETHYLACETAL
DMF-DMA
METHYL-8
METHYL-8 REAGENT
METHYL-8(R) REAGENT
N-DIMETHOXYMETHYL-N,N-DIMETHYLAMINE
N,N-DIMETHYLDIMETHOXYMETHYLAMINE
N,N-DIMETHYLFORMAMIDE DIMETHYL ACETAL
1,1-dimethoxy-n,n-dimethyl-methanamin
Dimethoxy(dimethylamino)methane
Dimethoxy-N,N-dimethylmethanamine
N-(Dimethoxymethyl)dimethylamine
N,N-Dimethylfirmanmidedimethylacetal
Trimethylamine, 1,1-dimethoxy-
DMFDMA (DMFA) | [EINECS(EC#)]
225-063-3 | [Molecular Formula]
C5H13NO2 | [MDL Number]
MFCD00008482 | [Molecular Weight]
119.16 | [MOL File]
4637-24-5.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colourless liquid | [Melting point ]
-85°C | [Boiling point ]
102-103 °C/720 mmHg (lit.) | [density ]
0.897 g/mL at 25 °C(lit.)
| [vapor pressure ]
34.5hPa at 20℃ | [refractive index ]
n20/D 1.396(lit.)
| [Fp ]
45 °F
| [storage temp. ]
Flammables area | [solubility ]
Miscible with most organic solvents. | [form ]
Solid | [pka]
5.00±0.50(Predicted) | [color ]
White to off-white | [PH]
7 (H2O) | [explosive limit]
1.3-17.7%(V) | [Water Solubility ]
hydrolysis | [Sensitive ]
Moisture Sensitive | [Detection Methods]
GC,NMR | [BRN ]
506020 | [Exposure limits]
ACGIH: TWA 200 ppm; STEL 250 ppm (Skin)
OSHA: TWA 200 ppm(260 mg/m3)
NIOSH: IDLH 6000 ppm; TWA 200 ppm(260 mg/m3); STEL 250 ppm(325 mg/m3) | [LogP]
0.750 (est) | [CAS DataBase Reference]
4637-24-5(CAS DataBase Reference) | [NIST Chemistry Reference]
Methanamine, 1,1-dimethoxy-N,N-dimethyl-(4637-24-5) | [Storage Precautions]
Moisture sensitive | [EPA Substance Registry System]
4637-24-5(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
F,Xn,Xi | [Risk Statements ]
R11:Highly Flammable.
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
R36/38:Irritating to eyes and skin .
R20:Harmful by inhalation.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R10:Flammable. | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37:Wear suitable protective clothing and gloves .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S33:Take precautionary measures against static discharges .
S29:Do not empty into drains .
S7/9:Keep container tightly closed and in a well-ventilated place . | [RIDADR ]
UN 3271 3/PG 2
| [WGK Germany ]
1
| [F ]
21 | [Autoignition Temperature]
155 °C | [TSCA ]
Yes | [HazardClass ]
3 | [PackingGroup ]
II | [HS Code ]
29225000 | [Toxicity]
LD50 orally in Rabbit: > 5000 mg/kg |
| Hazard Information | Back Directory | [Chemical Properties]
clear colourless liquid | [Uses]
1,1-Dimethoxy-N,N-dimethylmethanamine is used as a reagent in the formation of pyridine derivatives that exhibit inhibition against PI3 kinase p110α enzymes. | [Definition]
ChEBI: An acetal obtained by formal condensation of N,N-dimethylformamide with methanol. N,N-dimethylformamide dimethyl acetal is a derivatisation agent used in gas-chromatography applica
ions | [General Description]
Esterate M (N,N-Dimethylformamide dimethyl acetal, DMFDMA) is an methylating reagent. It has been used in methyl esterification of carboxylic acid and also in one-step derivatization of amino acids into N,N-Dimethylaminomethylene methyl esters. | [Flammability and Explosibility]
Highlyflammable | [reaction suitability]
reagent type: derivatization reagent
reaction type: Acylations
reagent type: derivatization reagent
reaction type: Esterifications |
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