| Identification | More | [Name]
1,1-Di-tert-butoxytrimethylamine | [CAS]
36805-97-7 | [Synonyms]
1,1-bis(1,1-dimethylethoxy)-n,n,n-trimethylamine
1,1-Di-tert-butoxy-N,N-dimethylmethylamine
1,1-DI-TERT-BUTOXYTRIMETHYLAMINE
N,N-DIMETHYLFORMAMIDE DI-T-BUTYL ACETAL
N,N-DIMETHYLFORMAMIDE DI-TERT-BUTYL ACETAL
N,N-DIMETHYLFORMAMIDE DI-TERT-BUTYL ACET AL, TECH., 90+%
N,N-DIMETHYLFORMAMIDE DI-TERT-BUTYL ACET AL, DERIVATIZATION GRADE
N,N-Dimethylformamide di-tert-butyl acetal, tech. 90%
N,N-Dimethylformamide Di-tert-butyl Acetal [for Esterification]
1,1-Di-tert-butoxytrimethylamine, 1,1-Di-tert-butoxy-N,N-dimethylmethylamine
N,N-Dimethyl-1,1-bis[(2-methylpropan-2-yl)oxy]methanamine
Di-tert-butoxy(dimethylamino)methane
N,N-Dimethyldi(tert-butyloxy)methanamine
N,N-Dimethyldi-tert-butoxymethanamine | [EINECS(EC#)]
253-222-7 | [Molecular Formula]
C11H25NO2 | [MDL Number]
MFCD00015002 | [Molecular Weight]
203.32 | [MOL File]
36805-97-7.mol |
| Chemical Properties | Back Directory | [Boiling point ]
56-57 °C8 mm Hg(lit.)
| [density ]
0.848 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.413(lit.)
| [Fp ]
93 °F
| [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
Miscible with toluene and benzene. | [form ]
clear liquid | [pka]
5.34±0.50(Predicted) | [color ]
Colorless to Almost colorless | [Specific Gravity]
0.848 | [Sensitive ]
Moisture Sensitive | [BRN ]
969629 | [InChI]
InChI=1S/C11H25NO2/c1-10(2,3)13-9(12(7)8)14-11(4,5)6/h9H,1-8H3 | [InChIKey]
DBNQIOANXZVWIP-UHFFFAOYSA-N | [SMILES]
C(OC(C)(C)C)(OC(C)(C)C)N(C)C | [CAS DataBase Reference]
36805-97-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R10:Flammable.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
UN 1993 3/PG 3
| [WGK Germany ]
3
| [F ]
10-21 | [HazardClass ]
3 | [PackingGroup ]
III | [HS Code ]
29221990 |
| Hazard Information | Back Directory | [Uses]
Reagent used for the preparation of indolizines via intermolecular cyclization of picolinium salts. | [Synthesis Reference(s)]
Synthetic Communications, 15, p. 723, 1985 DOI: 10.1080/00397918508063864 | [General Description]
N,N-Dimethylformamide di-tert-butyl acetal is an derivatizing reagent. | [reaction suitability]
reagent type: derivatization reagent
reaction type: Acylations | [Synthesis]
A mixture of 59.5 g (0.5 mol) of N, N-dimethylformamide dimethyl acetal and 147 mL (1.5 mol) of dry tert-butanol in a three-necked flask (250 mL) fitted with a thermometer magnetic stirrer, nitrogen inlet and a 33 x 1.9 cm silvered vacuum jacketed Goodloe column which was equipped with a reflux controlled take-off distilling head was heated at reflux for 1 hr, then 300 mg of 2,4,6-tri-tert-butylphenol was added. The reaction mixture was heated at 100-115°C for 48 hrs, during which time, at the rate of two drops/min, 56 mL of distillate was collected. Another 50 mL (0.52 mol) of tert-butanol was added to the reaction mixture, and the removal of methanol was continued for an additional 42 hrs to afford 64 mL of distillate. Distillation of the crude product with a similar but smaller column (20 x 1.4 cm) gave 53.2 g (52%) of N, N-Dimethylformamide di-tert-butyl acetal[1]. | [References]
[1] Mohacsi, E. “A New Synthetic Method for the Preparation of N,N-Dimethylformamide DI-Tert-Butyl Acetal.” Synthetic Communications 15 1 (1985): 723–725.
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