| Identification | More | [Name]
2-Aminopurine | [CAS]
452-06-2 | [Synonyms]
1H-PURINE-2-AMINE
2-AMINOPURINE
2-AMINOPURINE, HYDROCHLORIDE
1H-Purin-2-amine
2-amino-purin
9H-Purin-2-amine
SQ 22,451
SQ 22451
sq22451
iso-Adenine
2-Aminopurine
1H-Purine-2-amine
9H-Purin-2-amine
2-AMINOPURINE FREE BASE
1H-Purin-2-amine (9CI)
Purine, 2-amino.
4-aminopurine
7H-Purin-2-amine
2-Amino-1H-purine
2-Amino-7H-purine
2-Amino-9H-purine | [EINECS(EC#)]
207-197-4 | [Molecular Formula]
C5H5N5 | [MDL Number]
MFCD07357244 | [Molecular Weight]
135.13 | [MOL File]
452-06-2.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powder | [Melting point ]
280-282 °C (lit.) | [Boiling point ]
238.81°C (rough estimate) | [density ]
1.3795 (rough estimate) | [refractive index ]
1.7000 (estimate) | [storage temp. ]
2-8°C
| [solubility ]
Aqueous Acid (Slightly), Methanol (Slightly, Heated) | [form ]
Amorphous Powder | [pka]
8.02±0.20(Predicted) | [color ]
Light beige | [biological source]
synthetic | [Usage]
A probe of structural dynamicas and charge transfer in DNA | [Stability:]
Hygroscopic | [InChIKey]
MWBWWFOAEOYUST-UHFFFAOYSA-N | [CAS DataBase Reference]
452-06-2(CAS DataBase Reference) | [NIST Chemistry Reference]
Purine, 2-amino-(452-06-2) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S22:Do not breathe dust .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [RTECS ]
UO7475000
| [HS Code ]
29349990 | [Toxicity]
mmo-sat 100 mg/PLATE MUREAV 111,283,83 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powder | [Uses]
2-Aminopurine has been used to inhibit eukaryotic initiation factor-2α (eIF2α)-phosphorylation of osteoarthritis (OA) chondrocytes. | [Uses]
A probe of structural dynamicas and charge transfer in DNA | [Uses]
A probe of structural dynamics and charge transfer in DNA . | [Definition]
ChEBI: The parent compound of the 2-aminopurines, comprising a purine core carrying an amino substituent at the 2-position. | [Biochem/physiol Actions]
2-Aminopurine (2AP) is an analog of guanosine and adenosine, which can base pair with cytosine and thymine. It is used as a fluorescent probe in nucleic acid structure and dynamics. 2-Aminopurine (2-AP) inhibits double-stranded RNA-dependent protein kinase, protein kinase R (PKR). | [Safety Profile]
Mutation data reported. Whenheated to decomposition it emits toxic fumes of NOx. |
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