| Identification | More | [Name]
N-Formylmorpholine | [CAS]
4394-85-8 | [Synonyms]
4-FORMYLMORPHOLINE
4-MORPHOLINECARBOXALDEHYDE
MORPHOLINE-4-CARBOXALDEHYDE
N-FORMYLMORPHOLINE
TIMTEC-BB SBB007670
4-Morpholinecarbaldehyde
Formmorpholime
Morpholine, 4-formyl-
N-Formylmorfolin
Morpholine-1-carboxaldehyde
N-FORMYLMORPHOLINE 99+%
N-FormylMorpholine(Nfm) | [EINECS(EC#)]
224-518-3 | [Molecular Formula]
C5H9NO2 | [MDL Number]
MFCD00006170 | [Molecular Weight]
115.13 | [MOL File]
4394-85-8.mol |
| Chemical Properties | Back Directory | [Appearance]
CLEAR YELLOW LIQUID | [Melting point ]
20-23 °C (lit.) | [Boiling point ]
236-237 °C (lit.) | [density ]
1.145 g/mL at 25 °C(lit.)
| [vapor pressure ]
0.03 hPa (20 °C) | [refractive index ]
n20/D 1.485(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
Store below +30°C. | [solubility ]
SOLUBLE | [form ]
Liquid | [pka]
-0.75±0.20(Predicted) | [color ]
Clear yellow | [PH]
10 (250g/l, H2O, 20℃) | [explosive limit]
1.2-8.2%(V) | [Water Solubility ]
SOLUBLE | [Sensitive ]
Hygroscopic | [BRN ]
110293 | [LogP]
-1.2 at 23℃ | [CAS DataBase Reference]
4394-85-8(CAS DataBase Reference) | [NIST Chemistry Reference]
N-Formylmorpholine(4394-85-8) | [EPA Substance Registry System]
4394-85-8(EPA Substance) |
| Safety Data | Back Directory | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [RTECS ]
QD9694000
| [Autoignition Temperature]
345 °C DIN 51794 | [TSCA ]
Yes | [HS Code ]
29349990 | [Toxicity]
LD50 orally in Rabbit: > 7360 mg/kg LD50 dermal Rabbit > 18400 mg/kg |
| Hazard Information | Back Directory | [Description]
4-Formylmorpholine is an excellent non-protonic solvent. It is widely used as a solvent and extractant for aromatics. It is used as a detergent for acid gases. In the field of organic synthesis, it can be used to prepare labelled 14C, 4-(trifluoromethyl)morpholine, 3-alkyl-2-chloro-5,6-dihydrobenzaldehyde, triple-biphenyldialdehyde and phenylpropargyl aldehyde. It plays an important role in the desulphurisation of natural gas, syngas, flue gas and petrol. | [Chemical Properties]
CLEAR YELLOW LIQUID | [Uses]
4-Formylmorpholine is widely used as a solvent and extracting agent for aromatics. It is used as a scrubbing agent for acidic gases. It is employed in the preparation of adenine hydrochloride labeled with 14C, 4-(trifluoromethyl)morpholine, 3-alkyl-2-chloro-5,6-dihydrobenzaldehyde and terphenyl dialdehyde. It plays an important role in the desulfurization of natural gas, synthetic gas, flue gas and gasoline. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 25, p. 199, 1960 DOI: 10.1021/jo01072a012 | [General Description]
Treatment of 4-formylmorpholine with sulphur tetrafluoride in the presence of potassium fluoride gives 4-(trifluoromethyl)morpholine in excellent yields. 4-Formylmorpholine reacts with series of 2-alkyl-2-cyclohexen-1-ones in the presence of POCl3 to give the corresponding 3-alkyl-2-chloro-5,6-dihydrobenzaldehydes and allylic alcohols (by-product). | [Flammability and Explosibility]
Nonflammable |
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