| Identification | More | [Name]
N-Acetylmorpholine | [CAS]
1696-20-4 | [Synonyms]
4-ACETYLMORPHOLINE
Acetylmorpholine
MORPHOLINE, 4-ACETYL-
N-ACETYLMORPHOLINE
4-acetyl-morpholin
N-1-Acetyl morpholine
N-Acetylmorfolin
N-Aetylmorpholine
1-morpholinoethanone
N-acetylmorpholine 4-acetylmorpholine
n-acetylmorfoline
4-ACETYLMORPHOLINE PURUM 98%
1-Morpholin-4-ylethanone
Methylmorpholino ketone | [EINECS(EC#)]
216-913-4 | [Molecular Formula]
C6H11NO2 | [MDL Number]
MFCD00006171 | [Molecular Weight]
129.16 | [MOL File]
1696-20-4.mol |
| Chemical Properties | Back Directory | [Appearance]
CLEAR COLOURLESS TO VERY SLIGHTLY YELLOW LIQUID | [Melting point ]
14 °C (lit.) | [Boiling point ]
240-245 °C
| [density ]
1.116 g/mL at 25 °C(lit.)
| [vapor pressure ]
2.2Pa at 20℃ | [refractive index ]
n20/D 1.483(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
Sealed in dry,Room Temperature | [form ]
clear liquid | [pka]
-0.72±0.20(Predicted) | [color ]
Colorless to Light yellow | [Specific Gravity]
1.116 | [Water Solubility ]
MISCIBLE | [BRN ]
111971 | [LogP]
-0.81 at 24℃ | [CAS DataBase Reference]
1696-20-4(CAS DataBase Reference) | [NIST Chemistry Reference]
Morpholine, 4-acetyl-(1696-20-4) | [EPA Substance Registry System]
1696-20-4(EPA Substance) |
| Questions And Answer | Back Directory | [Uses]
N-Acetylmorpholine is a very important pesticide intermediate. It is one of the main raw materials for the synthesis of agricultural fungicides enoylmorpholine and flumorpholine. |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36:Irritating to the eyes. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S39:Wear eye/face protection . | [WGK Germany ]
1
| [RTECS ]
QD7000000
| [TSCA ]
Yes | [HS Code ]
29349990 |
| Hazard Information | Back Directory | [Chemical Properties]
CLEAR COLOURLESS TO VERY SLIGHTLY YELLOW LIQUID | [Application]
N-acetylmorpholine is a kind of oxaza compound mainly used to synthesize medical disinfectant use in agriculture, Aromatics Extractive Project agents, and gas sweetening agents. | [Flammability and Explosibility]
Nonflammable | [Synthesis]
Acetic acid and morpholine Reactive Synthesis N-Acetylmorpholine, the first step generates alkylbenzyldimethylasaltsum salts and a strong exothermal reaction; both can carry out under normal temperature, the alkylbenzyldimethylasaltsum saltsum of generation is solid; The dehydration of second step alkylbenzyldimethylasaltsum saltsum generates N-acetyl morphine, is thermo-negative reaction, need at high temperature to carry out, and speed of response is slow. The rate-determining steps of acetic acid and morpholine Reactive Synthesis N-Acetylmorpholine are morpholine dehydration of salt, and high temperature and in time dehydration are favorable to raising the speed of response.
| [Purification Methods]
Distil it through an 8inch Fenske (glass helices packing, p 11) column with a manual take-off head. Purify it by fractional distillation. The hydrobromide has m 172-175o. [Brace J Am Chem Soc 75 357 1953, deBenneville et al. J Org Chem 21 1072 1956, Beilstein 27 III/IV 274.] |
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