Identification | More | [Name]
(R)-(-)-2-Amino-3-methyl-1-butanol | [CAS]
4276-09-9 | [Synonyms]
2-AMINO-3-METHYLBUTAN-1-OL D-2-AMINO-3-METHYL-1-BUTANOL D-VALINAL (-)-D-VALINOL D-(-)-VALINOL D-VALINOL (D)-VALINOL/(R)-(-)-2-AMINO-3-METHYL-1-BUTANOL H-D-VAL-OL (R)-(-)-2-AMINO-3-METHYL-1-BUTANOL (R)-(+)-2-AMINO-3-METHYL-1-BUTANOL (R)-2-AMINO-3-METHYL-1-BUTANOL (R)-(-)-2-AMINO-3-METHYLBUTAN-1-OL (R)-(-)-2-AMINO-3-METHYLBUTANOL R-VALINOL D-(-)-VALINOL 98% (R)-(-)-Z-Amino-3-Methyl-1-Butanol D-Val-ol D-(-)-Valinol,98% 1-Butanol, 2-amino-3-methyl-, (2R)- (R)-(-)-2-Amino-3-methyl-1-butanol | [EINECS(EC#)]
217-975-5 | [Molecular Formula]
C5H13NO | [MDL Number]
MFCD00064297 | [Molecular Weight]
103.16 | [MOL File]
4276-09-9.mol |
Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powde | [Melting point ]
35-36 °C(lit.) | [alpha ]
-16.5 º (c=10, EtOH) | [Boiling point ]
189-190 °C(lit.) | [density ]
0.931 g/mL at 20 °C(lit.)
| [refractive index ]
n20/D 1.455
| [Fp ]
194 °F
| [storage temp. ]
2-8°C
| [form ]
Low Melting Crystals or Crystalline Mass | [pka]
12.82±0.10(Predicted) | [color ]
White to light yellow | [optical activity]
[α]20/D 16°, c = 10 in ethanol | [Sensitive ]
Air Sensitive | [BRN ]
1719138 | [InChIKey]
NWYYWIJOWOLJNR-YFKPBYRVSA-N | [CAS DataBase Reference]
4276-09-9(CAS DataBase Reference) | [Storage Precautions]
Air sensitive;Store under nitrogen |
Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36/37:Wear suitable protective clothing and gloves . S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [F ]
10-34 | [HS Code ]
29221990 |
Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powde | [Uses]
D-Valinol is used as a reagent in the synthesis of the HIV type 1 integrase inhibitor Elvitegravir (E509000). D-Valinol is also used in the preparation of novel 2-(alkylmorpholin-4-yl)-6-(3-fluoropyridin-4-yl)-pyrimidin-4(3H)-ones as orally active GSK-3β inhibitors for Alzheimer''s disease. |
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