Identification | Back Directory | [Name]
THIONICOTINAMIDE ADENINE DINUCLEOTIDE | [CAS]
4090-29-3 | [Synonyms]
THIO-NAD Thio-NAD/S-NAD THIONICOTINAMIDE-DPN Thionicotinamide-NAD Thionicotinamide-DPN oxidized form THIONICOTINAMIDE ADENINE DINUCLEOTIDE Thio-Nicotinamide Adenine Dinuclotide Thino-Nicotinamide Adenine Dinuclotide 3-Thionicotinamide adenine dinucleotide 3-Thiocarbamoylpyridine adenine dinucleotide Adenosine5'-(trihydrogen diphosphate), P'? Thio-NAD Thionicotinamide adenine dinucleotide Thionicotinamide Adenine Dinucleotide(THIO-NAD) β-ThionicotinaMide adenine dinucleotide, Oxidized forM β-Thionicotinamide adenine dinucleotide, 90%, Oxidized form Thio-Nicotinamide-Adenine Dinucleotide, Oxidized (Thio-NAD). beta-Thionicotinamide adenine dinucleotide, oxidised form 92+% 5'-ester with 3-(aMinothioxoMethyl)-1-b-D-ribofuranosylpyridiniuM, inner salt ThionicotinaMide Adenine Dinucleotide oxidized forM [for BiocheMical Research] | [EINECS(EC#)]
223-828-6 | [Molecular Formula]
C21H27N7O13P2S | [MDL Number]
MFCD00079609 | [MOL File]
4090-29-3.mol | [Molecular Weight]
679.49 |
Chemical Properties | Back Directory | [storage temp. ]
−20°C
| [form ]
powder to crystal | [color ]
Light orange to Yellow to Green | [InChIKey]
DQRRIGAXTAXHLR-NNYOXOHSSA-N | [SMILES]
O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP([O-])(=O)OC[C@@H]2[C@H]([C@@H](O)[C@H]([N+]3=CC=CC(C(=S)N)=C3)O2)O)O[C@H]1N1C=NC2C(=NC=NC1=2)N)O |&1:1,2,3,15,16,17,19,32,r| | [CAS DataBase Reference]
4090-29-3 |
Hazard Information | Back Directory | [Description]
Thionicotinamide adenine dinucleotide is an analog of NAD. Use of Thio-NAD instead of NAD as a substrate for NAD(+)-consuming enzymes is more advantageous since the reduced form of Thio-NAD exhibits a substantial increase in absorbance at 405 nM, the most commonly available wavelength on microplate readers. | [Chemical Properties]
Light yellow powder | [Uses]
Thionicotinamide adenine dinucleotide has been used as a substrate analog in S-adenosyl-l-homocysteine (AdoHcy) hydrolases (SAHH) inhibition assay and in NAD+ glycohydrolase activity. | [Application]
Thionicotinamide adenine dinucleotide (4090-29-3) is a NAD derivative used in the determination of Carnitine by an enzymic cycling method with carnitine dehydrogenase.
| [Biochem/physiol Actions]
Thionicotinamide adenine dinucleotide (sNAD) is an analog of coenzyme nicotinamide adenine dinucleotide (NAD) and NADH. sNAD is a potential inhibitor of NAD+ kinase. NAD+ kinase modulates NAD levels, contributing to cytotoxicity in cancer cells. | [storage]
Transport product sealed, dry, and protected from light at ambient temperature. Store product dry and protected from light. For long term storage keep below -20℃. |
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