成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

ChemicalBook--->CAS DataBase List--->3895-92-9

3895-92-9

3895-92-9 Structure

3895-92-9 Structure
IdentificationBack Directory
[Name]

CHELERYTHRINE CHLORIDE
[CAS]

3895-92-9
[Synonyms]

TODDALIN
CHELERYTHRINE
CHELERYTHRIN CL
Chelerythrine Cl
TODDALIN CHLORIDE
CHELERYTHRIN CHLORIDE
Chelerythrine cloride
Chelerythrine chloride
CHELERYTHRINE CHLORIDE(P)
CHELERYTHRINE CHLORIDE(RG)
Chelerythrine chloride,98%
chelerythrinehydrochloride
1,2-DIMETHOXY-12,[1,3]-BENZODIOXOLO[5,6-C]PHENANTHRIDINIUM CHLORIDE
3)benzodioxolo(5,6-c)phenanthridinium,1,2-dimethoxy-12-methyl-(chloride
1,2-DIMETHOXY-12-METHYL[1,3]BENZODIOXOLO[5,6-C]PHENANTHRIDINIUM CHLORIDE
1,2-Dimethoxy-N-methyl-[1,3]benzodioxolo[5,6-c]phenanthridinium chloride
[1,3]Benzodioxolo[5,6-c]phenanthridiniuM, 1,2-diMethoxy-12-Methyl-, chloride
[1,3]Benzodioxolo[5,6-c]phenanthridinium, 1,2-dimethoxy-12-methyl-, chloride (1:1)
1,2-diMethoxy-12-Methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridin-12-iuM chloride
Chelerythrine chloride1,2-Dimethoxy-N-methyl-[1,3]benzodioxolo[5,6-c]phenanthridinium chloride
[EINECS(EC#)]

223-444-9
[Molecular Formula]

C21H18ClNO4
[MDL Number]

MFCD00060717
[MOL File]

3895-92-9.mol
[Molecular Weight]

383.82
Chemical PropertiesBack Directory
[Appearance]

yellow to orange solid
[Melting point ]

195-205 °C
[storage temp. ]

−20°C
[solubility ]

DMSO: ≥10 mg/mL
[form ]

powder
[color ]

yellow to orange
[Stability:]

Hygroscopic
[InChIKey]

WEEFNMFMNMASJY-UHFFFAOYSA-M
Hazard InformationBack Directory
[Chemical Properties]

yellow to orange solid
[Description]

Chelerythrine is a potent, cell permeable inhibitor of protein kinase C (IC50 = 660 nM) that does not inhibit tyrosine protein kinases, cAMP-dependent protein kinase, or calcium/calmodulin-dependent protein kinase. Chelerythrine also inhibits Bcl-xL function (IC50 = 1.5 μM) by displacing Bax binding, inducing apoptosis in several cancer cell lines. Chelerythrine can also have PKC-independent effects, activate p38 MAP kinase and JUNK signaling pathways, and induce apoptosis in cancer cells both in vitro and in vivo.
[Uses]

Chelerythrine Chloride is a cell permeable protein kinase C (PKC) inhibitor.
[General Description]

Naturally occurring alkaloid. Cell-permeable, selective inhibitor of protein kinase C (IC50 = 660 nM). Acts on the catalytic domain irrespective of the attachment of the regulatory domain. Material is a competitive inhibitor with respect to the phosphate acceptor and a non-competitive inhibitor with respect to ATP. Over ten-fold more potent than H-7, HCl (Cat. No. 371955). Inhibits thromboxane formation and phosphoinositide metabolism in platelets. Also induces apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells.
[Biochem/physiol Actions]

Cell permeable: yes
[storage]

Store at -20°C
[References]

1. j. m. herbert, j. m. augereau, j. gleye and j. p. maffrand, biochem biophys res commun 1990, 172, 993-999. 2. w. d. jarvis, a. j. turner, l. f. povirk, r. s. traylor and s. grant, cancer res 1994, 54, 1707-1714. 3. j. vrba, p. dolezel, j. vicar, m. modriansky and j. ulrichova, toxicol in vitro 2008, 22, 1008-1017. 4. m. vogler, k. weber, d. dinsdale, i. schmitz, k. schulze-osthoff, m. j. dyer and g. m. cohen, cell death differ 2009, 16, 1030-1039. 5. r. yu, s. mandlekar, t. h. tan and a. n. kong, j biol chem 2000, 275, 9612-9619. 6. s. yamamoto, k. seta, c. morisco, s. f. vatner and j. sadoshima, j mol cell cardiol 2001, 33, 1829-1848.
Safety DataBack Directory
[Hazard Codes ]

Xn,Xi
[Risk Statements ]

20/21/22-36/37/38-36/37
[Safety Statements ]

26-36-36/37
[RIDADR ]

UN 1544PSN1 6.1 / PGII
[WGK Germany ]

3
[RTECS ]

FL9200000
[HS Code ]

29349990
[Toxicity]

mouse,LD50,intravenous,18500ug/kg (18.5mg/kg),Planta Medica. Vol. 43, Pg. 161, 1981.
Spectrum DetailBack Directory
[Spectrum Detail]

CHELERYTHRINE CHLORIDE(3895-92-9)MS
CHELERYTHRINE CHLORIDE(3895-92-9)1HNMR
3895-92-9 suppliers list
Company Name: Shaanxi Dideu Medichem Co. Ltd
Tel: +86-029-81138252 +86-18789408387 , +86-18789408387
Website: http://www.is0513.com/manufacturer/shaanxi-dideu-medichem-222/
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Website: www.is0513.com/ShowSupplierProductsList30845/0.htm
Company Name: career henan chemical co
Tel: +86-0371-86658258 +8613203830695 , +8613203830695
Website: www.coreychem.com/
Company Name: Chengdu GLP biotechnology Co Ltd
Tel: 028-87075086 13350802083 , 13350802083
Website: www. GLP-China.com
Company Name: Chengdu Biopurify Phytochemicals Ltd.
Tel: +8618080483897 , +8618080483897
Website: www.phytopurify.com
Company Name: Nanjing Dolon Biotechnology Co.,Ltd.
Tel: 18905173768
Website: www.is0513.com/ShowSupplierProductsList31215/0.htm
Company Name: Hubei xin bonus chemical co. LTD
Tel: 86-13657291602
Website: www.is0513.com/ShowSupplierProductsList1549548/0.htm
Company Name: BOC Sciences
Tel: +1-631-485-4226
Website: www.bocsci.com/
Company Name: Chongqing Chemdad Co., Ltd
Tel: +86-023-6139-8061 +86-86-13650506873 , +86-86-13650506873
Website: http://www.chemdad.com/
Company Name: Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
Tel: +8613580539051 , +8613580539051
Website: www.yuhengpharm.com
Company Name: Wuhan ChemNorm Biotech Co.,Ltd.
Tel: +86-27-8439 4403 18971486879 , 18971486879
Website: www.chemnorm.com
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000 , +1-00000000000
Website: https://www.targetmol.com/
Company Name: Hubei Ipure Biology Co., Ltd
Tel: +8613367258412 , +8613367258412
Website: www.ipurechemical.com
Company Name: Aktin Chemicals, Inc.
Tel: 028-85159085
Website: www.aktinchem.com
Company Name: Apeloa Pharmaceutical Co., Ltd.
Tel: +86-0571-87635730 +8615858229168 , +8615858229168
Website: http://www.apeloa.com/En/
Company Name: Dayang Chem (Hangzhou) Co.,Ltd.
Tel: 571-88938639 +8617705817739 , +8617705817739
Website: https://www.dycnchem.com/
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105 , +1-13798911105
Website: https://www.invivochem.com/
Company Name: Hebei baicao biology science and technology co., ltd
Tel: +86-19131911055 +8617824879454 , +8617824879454
Website: www.is0513.com/ShowSupplierProductsList1099453/0.htm
Tags:3895-92-9 Related Product Information
133052-90-1 136194-77-9 123-78-4 12707-58-3 137592-45-1 137592-47-3 154675-18-0 74-87-3 218-01-9 34316-15-9 92-44-4 7651-83-4 229-87-8 230-27-3