| Identification | More | [Name]
Ethyl 4,4,4-trifluoroacetoacetate | [CAS]
372-31-6 | [Synonyms]
4,4,4-TRIFLUORO-3-OXOBUTANOIC ACID ETHYL ESTER
4,4,4-TRIFLUOROACETOACETIC ACID ETHYL ESTER
AKOS B020306
ETHYL 3-OXO-4,4,4-TRIFLUOROACETOACETATE
ETHYL 3-OXO,4,4,4-TRIFLUOROBUTYRATE
ETHYL 4,4,4-TRIFLUORO-3-OXOBUTANOATE
ETHYL 4,4,4-TRIFLUOROACETOACETATE
ETHYL 4,4,4-TRIFLUOROACETOACTATE
ETHYL TRIFLUOROACETOACETATE
TIMTEC-BB SBB008825
TRIFLUOROACETOACETIC ACID ETHYL ESTER
4,4,4-trifluoro-3-oxo-butanoicaciethylester
Acetoacetic acid, 4,4,4-trifluoro-, ethyl ester
Acetoacetic acid, 4-trifluoro-, ethyl ester
Butanoicacid,4,4,4-trifluoro-3-oxo-,ethylester
Ethyl (trifluoroacetyl)acetate
Ethyl gamma,gamma,gamma-trifluoroacetoacetate
Ethyl omega,omega,omega-trifluoroacetoacetate
Ethyl4,4,-Trifluoroacetoacetate
Ethyltrifluoroacetoacetate,98+% | [EINECS(EC#)]
206-750-7 | [Molecular Formula]
C6H7F3O3 | [MDL Number]
MFCD00000424 | [Molecular Weight]
184.11 | [MOL File]
372-31-6.mol |
| Chemical Properties | Back Directory | [Appearance]
Clear liquid | [Melting point ]
-39 °C
| [Boiling point ]
129-130 °C(lit.)
| [density ]
1.259 g/mL at 25 °C(lit.)
| [vapor pressure ]
8hPa at 20℃ | [refractive index ]
n20/D 1.375(lit.)
| [Fp ]
84 °F
| [storage temp. ]
Flammables area | [solubility ]
10g/l | [form ]
Liquid | [pka]
7.76±0.10(Predicted) | [color ]
Clear colorless to slightly yellow | [Specific Gravity]
1.259 (20/4℃) | [PH]
6.2 (10g/l, H2O, 20℃) | [Water Solubility ]
10 g/L (20 ºC) | [Usage]
Intermediate for agro chemicals and pharmaceuticals (mefloquine). Product Data Sheet | [Detection Methods]
GC | [BRN ]
608353 | [InChIKey]
OCJKUQIPRNZDTK-UHFFFAOYSA-N | [CAS DataBase Reference]
372-31-6(CAS DataBase Reference) | [NIST Chemistry Reference]
Butanoic acid, 4,4,4-trifluoro-3-oxo-, ethyl ester(372-31-6) | [EPA Substance Registry System]
372-31-6(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,F,C,Xi | [Risk Statements ]
R10:Flammable.
R22:Harmful if swallowed.
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S16:Keep away from sources of ignition-No smoking . | [RIDADR ]
UN 3272 3/PG 3
| [WGK Germany ]
2
| [Hazard Note ]
Flammable/Corrosive | [TSCA ]
T | [HazardClass ]
3 | [PackingGroup ]
III | [HS Code ]
29183000 |
| Hazard Information | Back Directory | [Chemical Properties]
Clear liquid | [Uses]
Ethyl 4,4,4-trifluoroacetoacetate is used in the synthesis of fluorinated 2-thiouracil analogs as antithyroid agents.
| [Uses]
Intermediate for agro chemicals and pharmaceuticals (mefloquine). Product Data Sheet | [Uses]
Widely used in the synthetic process of medicine, pesticides and organic intermediate. | [Flammability and Explosibility]
Flammable | [Synthesis]
With an ethanol solution of sodium ethoxide as a catalyst and in the presence of an organic solvent, ethyl trifluoroacetate and ethyl acetate are subjected to a Claisen condensation reaction, and ethyl 4,4,4-trifluoroacetoacetate is synthesized. |
| Spectrum Detail | Back Directory | [Spectrum Detail]
Ethyl 4,4,4-trifluoroacetoacetate(372-31-6)MS
Ethyl 4,4,4-trifluoroacetoacetate(372-31-6)1HNMR
Ethyl 4,4,4-trifluoroacetoacetate(372-31-6)13CNMR
Ethyl 4,4,4-trifluoroacetoacetate(372-31-6)IR1
Ethyl 4,4,4-trifluoroacetoacetate(372-31-6)Raman
|
|
|