| Identification | More | [Name]
4-Bromo-2-fluoroaniline | [CAS]
367-24-8 | [Synonyms]
4-BROMO-2-FLUOROANILINE
4-BROMO-2-FLUORO-PHENYLAMINE
AKOS BBS-00003609
Benzenamine, 4-bromo-2-fluoro-
2-Fluoro-4-Bromoaniline
Bromofluoroaniline4
-BROMO-2-FLUOROANILINE, 98%
4-Bromo-2-fluoroaniline,98+%
4-Bromo-2-fluoroaniline 99%
4-Bromo-2-fluoroaniline99%
4-bromo-2-fluoro-Benzenamine | [EINECS(EC#)]
206-685-4 | [Molecular Formula]
C6H5BrFN | [MDL Number]
MFCD00010221 | [Molecular Weight]
190.01 | [MOL File]
367-24-8.mol |
| Chemical Properties | Back Directory | [Appearance]
solid | [Melting point ]
40-42 °C | [Boiling point ]
103-108 °C (13 mmHg)
| [density ]
1.6196 (rough estimate) | [refractive index ]
1.4710 (estimate) | [Fp ]
220 °F
| [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [form ]
Crystalline Mass, Powder, Crystals and/or Chunks | [pka]
2.50±0.10(Predicted) | [color ]
Beige to light brown to brown-gray or gray | [Stability:]
Stable. Incompatible with acid chlorides, acid anhydrides, strong acids, strong oxidizing agents. | [Detection Methods]
HPLC | [BRN ]
2081089 | [InChIKey]
GZRMNMGWNKSANY-UHFFFAOYSA-N | [CAS DataBase Reference]
367-24-8(CAS DataBase Reference) | [NIST Chemistry Reference]
4-Bromo-2-fluoroaniline(367-24-8) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,T,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S36:Wear suitable protective clothing . | [RIDADR ]
UN2811 | [WGK Germany ]
3
| [Hazard Note ]
Toxic | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29214200 |
| Hazard Information | Back Directory | [Chemical Properties]
solid | [Uses]
4-Bromo-2-fluoroaniline can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes. | [Synthesis]
To a stirred solution of 4-bromo-2-fluoro-l -nitrobenzene (10 g, 45.5 mmol) in EtOH (50 mL)AVater (20 mL) was added iron (12.7 g, 230 mmol) and NH4C1 (24.3 g, 455 mmol). The reaction mixture was stirred at 90 ??C for 2 h. After 2 h the reaction mixture was filtered over Celite. The filter cake was washed with EtOH (300 mL), and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel chromatography (S1O2, Petroleum ether/EtOAc=10: l to 5: 1) to afford 4-bromo-2-fluoroaniline. |
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