Identification | More | [Name]
4-BENZYLPIPERIDINE | [CAS]
31252-42-3 | [Synonyms]
4-BENZYLPIPERIDINE 4-(PHENYLMETHYL)PIPERIDINE AKOS BBS-00003617 ALPHA-(4-PIPERIDYL)TOLUENE LABOTEST-BB LTBB000752 PHENYL(4-PIPERIDYL)METHANE 4-(phenylmethyl)-piperidin 4-benzyl-piperidin Piperidine, 4-(phenylmethyl)- Piperidine, 4-benzyl- 4-Benzylpiperidine99% | [EINECS(EC#)]
250-535-0 | [Molecular Formula]
C12H17N | [MDL Number]
MFCD00006006 | [Molecular Weight]
175.27 | [MOL File]
31252-42-3.mol |
Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
TM4728000
| [Hazard Note ]
Irritant | [TSCA ]
Yes | [HazardClass ]
IRRITANT | [HS Code ]
29333990 |
Hazard Information | Back Directory | [Chemical Properties]
CLEAR COLOURLESS TO YELLOW VISCOUS LIQUID | [Uses]
4-Benzylpiperidine was studied as acid corrosion inhibitor for iron. It was also used to study potential utility of dopamine-welective releaser as a treatment for cocaine dependence. In an assay of cocaine discrimination, 4-Benzylpiperidine had the most rapid onset and shortest duration of action. | [Uses]
Reactant for synthesis of: Antiproliferatives GABA uptake inhibitors Pyridines Histamine H3 antagonists Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer′s and neuronal vascular diseases Antiserotoninergic, antiplatelet, hemorheologic, antiarrythmic and antioxidant molecules via nucleophilic substitution | [Application]
Reactant for synthesis of: Antiproliferatives GABA uptake inhibitors Pyridines Histamine H3 antagonists Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer′s and neuronal vascular diseases Antiserotoninergic, antiplatelet, hemorheologic, antiarrythmic and antioxidant molecules via nucleophilic substitution | [Preparation]
4-Benzylpiperidine can be prepared by reacting 4-cyanopyridine with toluene. Catalytic hydrogenation of the pyridine ring then completes the synthesis. | [Synthesis Reference(s)]
Synthesis, p. 741, 1980 DOI: 10.1055/s-1980-29196 | [General Description]
4-Benzylpiperidine is dopamine-selective releaser. It is a potential candidate for treatments for cocaine dependence. | [Biochem/physiol Actions]
4-Benzylpiperidine inhibits the activity of rat brain monoamine oxidase-A and -B. |
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