| Identification | More | [Name]
Diphenylpiperidin-4-ylmethanol hydrochloride | [CAS]
1798-50-1 | [Synonyms]
ALPHA,ALPHA-DIPHENYL-4-PIPERIDINOMETHANOL, HYDROCHLORIDE
AZACYCLONOL HYDROCHLORIDE
DIPHENYL-PIPERIDIN-4-YL-METHANOLHYDROCHLORIDE
alpha-(4-piperidyl)benzhydrolhydrochloride
alpha,alpha-diphenyl-4-piperidinemethanohydrochloride
alpha,alpha-diphenyl-4-piperidinemethanolhydrochloride
frenquelhydrochloride
gamma-pipradolhydrochloride
alpha,alpha-diphenylpiperidine-4-methanol hydrochloride
AZACYCLONO HYDROCHLORIDE
ALPHA,ALPHA-DIPHENYL-4-PIPERIDINOMETHANOL HCL
AZACYCLONOL HCL
Azacylononl
A:acyclonol hydrochloride | [EINECS(EC#)]
217-284-9 | [Molecular Formula]
C18H22ClNO | [MDL Number]
MFCD00039039 | [Molecular Weight]
303.83 | [MOL File]
1798-50-1.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [HazardClass ]
IRRITANT | [HS Code ]
29333999 |
| Hazard Information | Back Directory | [Chemical Properties]
white to off-white crystalline powder | [Originator]
Frenquel,Merrell,US,1955 | [Manufacturing Process]
A mixture of 26 g (0.1 mol) of α-(4-pyridyl)-benzhydrol, 1.5 g of platinum
oxide, and 250 ml of glacial acetic acid is shaken at 50-60°C under hydrogen
at a pressure of 40-50 lb/in2. The hydrogenation is complete in 2 to 3 hours.
The solution is filtered and the filtrate evaprated under reduced pressure. The
residue is dissolved in a mixture of equal parts of methanol and butanone and
0.1 mol of concentrated hydrochloric acid is added. The mixture is cooled and
filtered to give about 30 g of α-(4-piperidyl)benzhydrol hydrochloride, MP 283-
285°C, as a white, crystalline substance.
The free base is readily obtained from the hydrochloride salt by treatment
with ammonia and when so obtained has a melting point of 160-161°C. | [Brand name]
Frenquel (Marion Merrell
Dow). | [Therapeutic Function]
Tranquilizer |
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