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ChemicalBook--->CAS DataBase List--->302543-62-0

302543-62-0

302543-62-0 Structure

302543-62-0 Structure
IdentificationMore
[Name]

Rosiglitazone hydrochloride
[CAS]

302543-62-0
[Synonyms]

ROSIGLITAZONE HYDROCHLORIDE 99%
5-[4-[2-[N-Methyl-N-(pyridinyl) amino]ethoxy]benzyl]thiazolidine-2,4-dione hydrochloride
Rosiglitazone hydrochloride
[EINECS(EC#)]

1308068-626-2
[Molecular Formula]

C18H19N3O3S.HCl
[MDL Number]

MFCD04112701
[Molecular Weight]

393.89
[MOL File]

302543-62-0.mol
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

≥39.4 mg/mL in DMSO; ≥2.81 mg/mL in H2O with gentle warming and ultrasonic; ≥51.2 mg/mL in EtOH with ultrasonic
[form ]

solid
[color ]

White to off-white
[CAS DataBase Reference]

302543-62-0(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319
[Precautionary statements ]

P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard InformationBack Directory
[Chemical Properties]

Rosiglitazone is a hypoglycemic drug developed by GS, and the revalent compounds are disclosed in European Patent EP 306228.
[Uses]

Rosiglitazone hydrochloride has better stability than rosiglitazone maleate, and is very suitable for application in the manufacture of common pharmaceutical preparations. It is a thiazolidinedione antidiabetic drug, which can effectively control blood sugar by improving insulin sensitivity.
[Biological Activity]

rosiglitazone is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the ppar receptors in fat cells.
[target]

TargetValue
PPAR
Spectrum DetailBack Directory
[Spectrum Detail]

Rosiglitazone hydrochloride(302543-62-0)1HNMR
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